| 血清白介素18 高敏C反应蛋白水平与冠心病的关系 |
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| 引用本文： | 陈东芳,赵延恕,贾建桃. 血清白介素18 高敏C反应蛋白水平与冠心病的关系[J]. 长治医学院学报, 2009, 23(3) |
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| 作者姓名： | 陈东芳 赵延恕 贾建桃 |
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| 作者单位： | 长治医学院附属和平医院干保科,046000;中南大学湘雅二院;长治医学院病理生理学教研室 |
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| 基金项目： | 长治医学院附属和平医院科研基金 |
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| 摘 要： | 目的:探讨冠心病患者血清白介素18、高敏C反应蛋白水平与冠心病临床表现及冠状动脉病变程度的关系.方法:63例冠心病患者和对照组16例,分为ACS组、SAP组和对照组. 所有入选对象均进行冠状动脉造影检查,冠心病患者分为单支病变组、双支病变组、多支病变组.检测所有对象血清白介素18及高敏C反应蛋白水平.结果:随着冠心病病情危险程度的升高, 白介素 18、高敏C反应蛋白水平逐渐升高,各组间差别具有统计学意义(P<0.01,P<0.05) ,两者水平变化经Pearson相关性检验呈正的直线相关关系,(r=0.425,P<0.05).随着冠脉病变程度的加重,两者水平变化差别无统计学意义(P>0.05).结论:白介素18、高敏C反应蛋白水平可以作为冠心病危险性的预测因子.两者血清水平与冠状动脉病变程度无明显相关,与冠状动脉造影联合使用可以更好的评估冠心病患者的预后.
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| 关 键 词： | 白介素18 高敏C反应蛋白 冠心病 急性冠脉综合征 冠状动脉造影 |
Interleukin 18 and High Sensitive C-reactive Protein in Ralation to Coronary Heart Disease |
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| Chen Dongfang,Zhao Yanshu,Jia Jiantao. Interleukin 18 and High Sensitive C-reactive Protein in Ralation to Coronary Heart Disease[J]. Journal of Changzhi Medical College, 2009, 23(3) |
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| Authors: | Chen Dongfang Zhao Yanshu Jia Jiantao |
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| Affiliation: | Chen Dongfang,Zhao Yanshu,Jia Jiantao Department of Geriatrics,Heping Hospital,Changzhi Medical College |
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| Abstract: | Objective: To investigate the relationship between IL-18,hs-CRP level and clinical manifestation of coronary heart disease and to investigate the relationship between them and severity of coronary artery lesions at the same time.Methods: 63 patients of coronary heart diseases and 16 healthy control persons were enrolled.They were divided into three groups: ACS group,SAP group and the control group.All cases were performed coronary angiography.The patients were divided into three groups as follows:single ves... |
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| Keywords: | Interleukin 18 High sensitive C-reactive protein Coronary heart diseases Acute coronary syndrome Coronary angiography |
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