高血压患者血压变异性与左心室肥厚的关系

【目的】探讨原发性高血压患者血压变异性与左心室肥厚的关系。【方法】60例原发性高血压患者分别进行超声心动图和动态血压监测，根据左心室重量指数（LVMI）分为左心室肥厚（LVH）组和无LVH组，分析比较两组间的血压均值和血压变异性。【结果】LVH组24 h平均收缩压（24hSBP）、24 h平均舒张压（24hDBP）及白昼收缩压（dSBP）与夜间收缩压（nSBP）、白昼舒张压（dDBP）均显著高于无LVH组，且差异显著（ P ＜0．05）；LVH组血压变异性各指标除白昼舒张压标准差（dDSD）外，均比无LVH组增大，差异显著（ P ＜0．05）。【结论】原发性高血压患者LVH的发生和血压变异性密切相关，血压变异性增高对左心室肥厚风险有一定预测价值。

Relationship Between Blood Pressure Variability and Left Ventricular Hypertrophy in Patients with Essential Hypertension

[Objective] To explore the correlation between blood pressure variability and left ventricular hypertrophy（LVH） in patients with essential hypertension .[Methods] Totally 60 patients with essential hy-pertension were monitored by echocardiogram and dynamic blood pressure .According to left ventricular mass index（LVMI） ,all patients were divided into left ventricular hypertrophy （LVH） group and non-LVH group . Mean blood pressure and blood pressure variability were compared between two groups .[Results] The 24h systolic blood pressure （24hSBP） ,24h diastolic blood pressure （24hDBP） ,daytime systolic blood pressure （dSBP） ,daytime diastolic blood pressure （dDBP） ,night systolic blood pressure （nSBP） and night diastolic blood pressure（nDBP） in LVH group were markedly higher than those in non-LVH group ,and there was sig-nificant difference（ P 〈0 .05） .Compared with non-LVH group ,the indexes of blood pressure variability in LVH group except dDBP were increased ,and there was significant difference（ P 〈0 .05） .[Conclusion] The occurrence of LVH in patients with essential hypertension is closely related to blood pressure variability .The increasing of blood pressure variability is valuable for predicting the risk of LVH .