珂立苏联合经鼻同步间歇指令通气治疗新生儿肺透明膜病疗效观察 |
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引用本文: | 张爱珍,何青,朱玉芳,张菲.珂立苏联合经鼻同步间歇指令通气治疗新生儿肺透明膜病疗效观察[J].湖南医学,2014(2):302-304. |
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作者姓名: | 张爱珍 何青 朱玉芳 张菲 |
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作者单位: | 湖南省常德市第一人民医院新生儿科,湖南常德415003 |
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摘 要: | 【目的】探讨注射型牛肺表面活性物质(珂立苏)联合经鼻同步间歇指令通气(NSIM V )对新生儿肺透明膜病(HMD)的治疗效果及安全性。【方法】对37例HMD患儿予珂立苏联合NSIMV进行监护治疗,观察其疗效及并发症。【结果】PS联合NSIM V能明显改善HMD患儿呼吸、心率及血气各项指标,与治疗前比较差异有统计学意义( P <0.05),且无严重并发症。【结论】珂立苏联合NSIM V治疗HMD安全有效,能减少气管插管比例及避免相关并发症,值得推广使用。
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关 键 词: | 透明膜病 治疗 肺疾病 治疗 呼吸 人工 |
Clinical Research on PS Combined with Transnasal Synchronized Intermittent Mandatary Ventilation for the Treatment of Neonatal Pulmonary Hyaline Membrane Disease |
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Institution: | ZHANG Ai-zhen , HE Qing , ZHU Yu-fang, et al ( Department of Neonatology, the People's Hospital of Changde City, Hunan 415003, Onina ) |
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Abstract: | Objective]To explore the efficacy and safety of pulmonary surfactant (PS) combined with nasal synchro-nized intermittent mandatory ventilation (Nsimv ) for the treatment of neonatal pulmonary hyaline membrane disease (HMD) .Methods] A total of 37 pediatric patients with HMD were treated with Kelisu and Nsimv .The efficacy and complications were observed .Results] PS combined with Nsimv could improve respiration ,heart rate and blood gas in-dexes of HMD patients ,and there was significant difference between before and after treatment ( P〈0 .05) .No serious complication occurred .Conclusion] PS combined with Nsimv for the treatment of HMD is safe and effective ,and can re-duce endotracheal intubation ratio and avoid the related complications .Therefore it is worth popularizing . |
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Keywords: | Hyaline Membrane Disease/TH Lung Diseases/TH Respiration Artificial |
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