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一起草菇中毒的急性毒性研究
引用本文:李军涛,张全新,杨光宇,李文学,朱伟. 一起草菇中毒的急性毒性研究[J]. 中国卫生检验杂志, 2011, 0(1)
作者姓名:李军涛  张全新  杨光宇  李文学  朱伟
作者单位:广州市疾病预防控制中心;
摘    要:目的:探讨草菇中毒的原因并对其毒性进行评价。方法:SPF级NIH小鼠、Hartly白化豚鼠经口灌胃(0.2 ml/10.0 g.bw)、腹腔注射(0.2 ml/10.0 g.bw)染毒,连续观察7 d。结果:草菇生品对NIH小鼠经口灌胃染毒未见明显毒性;对Hartly豚鼠经口灌胃染毒可出现明显中毒症状,并引起动物死亡。草菇生品对NIH小鼠腹腔注射染毒有较强毒性,草菇熟品未见引起中毒反应。结论:草菇生品有一定的毒性,可能引起中毒反应。

关 键 词:草菇  急性经口毒性  腹腔注射  

Study on acute toxicity of a straw mushroom poisoning
LI Jun-tao,ZHANG Quan-xin,YANG Guang-yu,LI Wen-xue,ZHU Wei. Study on acute toxicity of a straw mushroom poisoning[J]. Chinses Journal of Health Laboratory Technology, 2011, 0(1)
Authors:LI Jun-tao  ZHANG Quan-xin  YANG Guang-yu  LI Wen-xue  ZHU Wei
Affiliation:LI Jun-tao,ZHANG Quan-xin,YANG Guang-yu,LI Wen-xue,ZHU Wei(Guangzhou Center for Disease Control anf Prevention,Guangzhou 510080,China)
Abstract:Objective:To study the cause of mushroom poisoning and evaluate its toxicity.Methods: NIH mice(SPF grade) and Hartly Albino guinea pigs were treated respectively with 0.2 ml/10.0 g.bw via intragastric administration and 0.2 ml/10.0 g.bw via intraperitoneal injection,and observed continuously for 7 days.Results: There is no significant toxicity in NIH mice treated with fresh mushroom via intragastric administration;however,there are obvious symptoms of poisoning and death in Hartly Albino guinea pigs treated...
Keywords:Straw mushroom  Oral toxicity test  Intraperitoneal injection  
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