| 肿瘤标志物联合检测对原发性肝癌的诊断价值 |
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| 引用本文： | 张丽娟,吴华颖,王晓鸿,舒晓春.肿瘤标志物联合检测对原发性肝癌的诊断价值[J].中国卫生检验杂志,2011(1). |
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| 作者姓名： | 张丽娟 吴华颖 王晓鸿 舒晓春 |
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| 作者单位： | 中山大学附属第五医院检验科; |
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| 摘 要： | 目的:探讨7种血清肿瘤标志物(TM)对肝癌的诊断价值,并筛选出对原发性肝癌(PHC)有价值的TM组合。方法:采用免疫化学发光法测定甲胎蛋白(AFP)、糖链抗原199(CA19-9)、糖链抗原125(CA125)、癌胚抗原(CEA)水平;用连续监测法测定α-L-岩藻糖苷酶(AFU)、r-谷氨酰转移酶(r-GT)、碱性磷酸酶(AKP)。共检测了78例PHC患者和92例肝硬化患者、75例肝炎组及58例健康成人。结果:平行试验敏感性达100%和系列试验特异性达99%的组合有AFP+CA125+r-GT、AFP+AKP+r-GT、AFP+AKP+r-GT+CA199、AFP+CA199+r-GT;总阳性似然比高的组合有AFP+CA125+AKP、AFP+CA199+AKP、AFP+AKP+r-GT。结论:对PHC患者合理的组合为AFP+CA125+AKP、AFP+CA199+AKP、AFP+AKP+r-GT。
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| 关 键 词： | 原发性肝癌 肿瘤标志物 联合检测 |
Diagnostic value of combined detection of serum tumor marker in primary hepatic carcinoma |
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| ZHANG Li-juan,WU Hua-ying,WANG Xiao-hong,SHU Xiao-chun.Diagnostic value of combined detection of serum tumor marker in primary hepatic carcinoma[J].Chinses Journal of Health Laboratory Technology,2011(1). |
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| Authors: | ZHANG Li-juan WU Hua-ying WANG Xiao-hong SHU Xiao-chun |
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| Institution: | ZHANG Li-juan,WU Hua-ying,WANG Xiao-hong,SHU Xiao-chun(Department of Clinical Laboratoy,the Fifth Affiliated Hospital of Sun Yat-sen University,Zhuhai 519000,China) |
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| Abstract: | |
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| Keywords: | Primary hepatic carcinoma Tumor marker Combined detection |
| 本文献已被 CNKI 等数据库收录！ |
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