递增负荷训练对大鼠骨骼肌肌浆网Na^＋,K^＋-ATP酶和Ca^2＋-ATP酶活性的影响

【目的】研究递增负荷训练对大鼠骨骼肌肌浆网Na＋,K＋-ATP酶和Ca2＋-ATP酶活性的影响。【方法】参照BEDFORD TG标准,采用跑台运动方式,建立大鼠递增负荷训练模型。将24只大鼠随机分为3组：正常对照组（n=8）、递增负荷运动4周组（n=8）和递增负荷运动6周组（n=8）。超速离心法提取大鼠骨骼肌肌浆网,测定肌浆网Na＋,K＋-ATP酶和Ca2＋-ATP酶的活性。【结果】递增负荷运动组Na＋,K＋-ATP酶和Ca2＋-ATP酶的活性较正常对照组显著升高（P〈0.05）。【结论】实验结果表明,一定时间的递增负荷训练可提升骨骼肌肌浆网Na＋,K＋-ATP酶和Ca2＋-ATP酶的活性。

Effects of incremental load training on the activity of Na+,K+-ATPase and Ca2+-ATPase in rats'skeletal muscle sarcoplasmic reticulum

【Objective】 To observe the effects of incremental load training on the activity of Na＋,K＋-ATPase and Ca2＋-ATPase in Rats＇skeletal muscle sarcoplasmic reticulum.【Methods】Consulting BEDFORD TG＇ standards,we established the motion models using treadmill running at different work intensities.Twenty-four SD rats were randomly divided into three groups： control group（n=8）,4-weeks＇incremental load training group（n=8）and 6-weeks＇incremental load training group（n=8）.Then rats＇ skeletal muscle sarcoplasmic reticulum were preparied and the activity of Na＋,K＋-ATPase and Ca2＋-ATPase were determined.【Results】The activity of Na＋,K＋-ATPase and Ca2＋-ATPase of incremental load training group are significantly higher than that of control group（P0.05） 【Conclusion】The results suggest that the activity of Na＋,K＋-ATPase and Ca2＋-ATPase in rats＇skeletal muscle sarcoplasmic reticulum are protected by incremental load training.