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支气管哮喘并发肺癌的联合手术治疗
引用本文:Liu J,Zhang G,Jiang G,Peng J,Wang D,He Q. 支气管哮喘并发肺癌的联合手术治疗[J]. 中华外科杂志, 2000, 38(3): 185-188
作者姓名:Liu J  Zhang G  Jiang G  Peng J  Wang D  He Q
作者单位:[1]北京医科大学人民医院胸外科 [2]呼吸内科
摘    要:目的 探讨支气管哮喘患者并发肺癌进行联合手术的可行性。方法 在根治性切除肺部肿瘤的同时,采用肺门神经彻底切断术治疗支气管哮喘。1例右上叶周围型肺癌,行右上肺叶切除、淋巴结清扫的同时作同侧肺门迷走神经和交感神经的彻底切断。另1例左上肺巨大中心型肺癌,行全肺切除后,摘出可保留的左下肺叶,采用自体肺移植技术将其重植于原左肺上叶位置。结果 随访至1999年11月底,2例已分别存活6年8个月及17个月。术后

关 键 词:哮喘 肺肿瘤 肺切除术 肺移植 并发症
修稿时间:1999-12-08

Surgery for lung cancer complicated by bronchial asthma
Liu J,Zhang G,Jiang G,Peng J,Wang D,He Q. Surgery for lung cancer complicated by bronchial asthma[J]. Chinese Journal of Surgery, 2000, 38(3): 185-188
Authors:Liu J  Zhang G  Jiang G  Peng J  Wang D  He Q
Affiliation:Department of Thoracic Surgery, People's Hospital, Beijing Medical University, Beijing 100044, China.
Abstract:Objective To assess surgery for lung cancercomplicated by bronchial asthma. Methods Lung hilum denervation wasperformed for asthma during radical resection of lung cancer. One patient with peri-pheralbronchogenic carcinoma in the right upper lobe underwent upper lobectomy and extensivedissection of lymph-nodes. Simultaneously, lung hilum denervation was done by completsampatation of the sympathetic and parasympathetic nerves around the lung hilum. Anotherpatient with central bronchogenic carcinoma in the left upper lobe underwent lungautotransplantation. Pneumonectomy was performed, and the tumor parts of the lung wereresected subseguantly and the preservable parts of the lung were replanted into the bed ofthe upper lobe. Results Follow-up showed that the two patients hadbeen alive with tumor free for 80 months and 17 months respectively and the time ofpostoperative mechanical ventilation was 4 and 18 hours. The frequency of asthma paroxysmdecreased and the severity attenuated. Parameters of blood gas and lung function wereimproved. Conclusions The poor lung function caused by asthma shouldnot be regarded as a contradiction for the remaval of lung cancer. Complete denevationaround the lung hilum during the radical resection of lung cancer may contribute to thebetter treatment of lung cancer and asthma.
Keywords:Asthma   Lung neoplasms   Pneumonectomy   Lungtransplantation
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