| 喹诺酮类抗菌药对金黄色葡萄球菌抗生素耐药质粒的消除作用 |
| |
| 引用本文： | 姚勤,陈小英,陈知本.喹诺酮类抗菌药对金黄色葡萄球菌抗生素耐药质粒的消除作用[J].中国药科大学学报,1992(4). |
| |
| 作者姓名： | 姚勤 陈小英 陈知本 |
| |
| 作者单位： | 中国医科大学生物研究中心
(姚勤，陈小英)，中国医科大学生物研究中心(陈知本) |
| |
| 摘 要： | 以喹诺酮类药物作为质粒消除剂,进行抗生素耐药质粒定位实验。通过10株金黄色葡萄球菌耐药株的实验,确定其中3株菌具有氯霉素、四环素和红霉素耐药质粒。并比较了喹诺酮类与SDS的消除作用,发现在不同浓度的消除剂及不同菌株中其消除作用不相同。
|
| 关 键 词： | 金黄色葡萄球菌 质粒消除 喹诺酮类 |
Elimination of Antibiotic-resistant Plasmids by Quinolones in Staphylococcus aureus |
| |
| Yao Qin,Chen Xiaoying,Chen Zhiben Biological Research Center.Elimination of Antibiotic-resistant Plasmids by Quinolones in Staphylococcus aureus[J].Journal of China Pharmaceutical University,1992(4). |
| |
| Authors: | Yao Qin Chen Xiaoying Chen Zhiben Biological Research Center |
| |
| Abstract: | Elimination of antibiotic-resistant plasmids in S. aureus by quinolones and SDS was reported. It was demonstrated that among ten tested strains of S. aureus, tetracycline, chloromycetin and erythromycin resistance plasmids were found in three strains 85094, 85040 and 90013. By comparing elimination rates for quinolone and SDS, it was revealed that the effect on plasmid elimination was variable under the condition of different concentrations of curing agents and different strains. |
| |
| Keywords: | S aureus Plasmid elimination Quinolone |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国药科大学学报》浏览原始摘要信息 |
| 点击此处可从《中国药科大学学报》下载免费的PDF全文 |
