| 膦甲酸钠治疗重症肝炎疗效观察 |
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| 引用本文： | 邱平,贾杰,陈所贤,何远学,许小珍,沈伟. 膦甲酸钠治疗重症肝炎疗效观察[J]. 中国热带医学, 2001, 1(2): 124-125 |
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| 作者姓名： | 邱平 贾杰 陈所贤 何远学 许小珍 沈伟 |
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| 作者单位： | 海南省人民医院,海口市,570311 |
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| 基金项目： | 海南省卫生厅重点资助项目（99－01号） |
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| 摘 要： | 目的 探讨膦甲酸钠治疗重症肝炎的疗效。方法 将1999年12月至2001年1月收治的43例重症肝炎，分为两组，A组为对照组在综合疗法上加用促肝细胞生长素治疗，B组为治疗组在A组疗法上加用膦甲酸钠治疗。结果 A组22例患中治愈1例，好转ll例，无效10例。B组2l例患中治愈ll例，好转7例，无效3例。B组乙肝病毒指标HBeAg阴转率68．7％，HBVDNA阴转率77．7％，而A组均为零。结论 膦甲酸钠对乙肝病毒有确切抑制作用，治疗重症肝炎疗效显。
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| 关 键 词： | 膦甲酸钠 药物治疗 重症病毒性肝炎 促肝细胞生长素 抗病毒药 |
| 文章编号： | 1009-9727(2001)02-0124-02 |
| 修稿时间： | 2001-05-14 |
Observation of the therapeutic effects of foscarnet on patients with severe hepatitis |
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| QIU Ping,JIA Jie,CHEN Shuo-xian,et al.. Observation of the therapeutic effects of foscarnet on patients with severe hepatitis[J]. China Tropical Medicine, 2001, 1(2): 124-125 |
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| Authors: | QIU Ping JIA Jie CHEN Shuo-xian et al. |
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| Abstract: | Objective To evaluate the therapeutic effects of foscarnet in severe hepatitis. Methods Forty -three cases of severe hepatitis were divided into Group A and Group B during December 1999 to January 2001. Group A was the control group, which received synthetic treatment and hepatocyte Growth - promoting Factors. Group B was the treatment group, which received group A treatment and foscarnet. Results One of 21 cases in group A was curative,11 cases improved,10 cases inefficient.In group B,11 cases curative,7 casese improved,3 cases inefficient.In group B,68.7%(11/16) HBeAg and 77.7%(14/18)HBVDNA were converted negative,but both in group A were 0% . Conclusions Foscarnet could inhibit HBV replication and had beneficial therapeutic effects on severe hepatitis. |
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| Keywords: | Foscarnet Severe hepatitis Antivirus. |
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