肺癌磁共振信号模式的建立

前瞻分析肺癌的MRI信号结构,建立磁共振信号模式。材料和方法：以肺癌病灶为中心横断面T1、T2加权成像。分析肿块内部结构，包括有无坏死、空洞、出血及信号结构特点等。并以肿块相邻层面之椎体信号作参照，将肿块信号分成高、中、低三个等级。在此基础上根据肿块在多回波序列上的变化趋势，描绘模拟肺癌肿块的信号曲线。全部（95例）病例，均经病理证实，鳞癌43例、腺癌36例、未分化癌10例、鳞腺混合癌4例、肺泡细胞癌2例。结果：T2WI上肿瘤实体内点簇状高信号区可鉴别腺癌与鳞癌；T1WI及T2WI长回波第三、四回波对肺癌组织类型的鉴别有帮助；鳞癌在多回波序列上表现为先升后降的（A类）信号模式，腺癌及其他类肺癌在T2WI上多为较持续的高信号状态（B类）曲线。结论：通过分析信号结构及其变化模式，可大体区分几种主要的肺癌组织类型。

The Establishment of MRI Signal Format on Different Kinds of Bronchogenic Carcinoma

Purpose: The MRI signal structures of various kinds of bronchogenic carcinomas were analized prospectively and then followed by the formation of the definite MRI signal format. Materials and Methods: The T1 and T2 weighted MR images were obtained by cutting through,the center of bronchogenic carcinoma on axial sections. Taking the signal intensities of the nearby vertebral body as control to analize the internal structures of the tumor including the characteristic signals of necrosis, cavity, hemorrhage etc with outcoming of the high, intermediate and low signal intensities for diagnosing the tuniors. The signal curve of the format for the bonchogenic carcinoma could be obtained thus through the tendency of changes shown on the multiple echo sequences. 95 cases (all were proved pathologically) including squamous cell carcinoma 43, adenocarcinoma 36, anaplastic carcinoma 10, mixed squamous cell adenocarcinoma 4, alveolar cell carcinoma 2 were studied by MRI prospectively. Results: The intratunioral stippling high signal intensities on T2 weighted images could differentiate adenocarcinoma from squanious cell carcinoma. The signals of the 3rd and 4th echoes of long TE shown on TI weighted and T2 weighted unages could have some favors on tissue differentiation of the types for bronchogenic carcinomas. Squamous cell carcinoma belongs to type A giving the early high and later low signal intensities on multiple echo sequences. On the other hand, adenocarcinoma and other kinds of bronchogenic carcinoma could show rather persistent high signal intensities on T2 weighted images, type B. Conclusion: The probable acknowledgement of tissue types of the several main kinds of bronchogenic carcinoma could be obtained by analizing their changes and structures shown on MRI signal intensity format.