| 异丙肾上腺素复制大鼠心衰模型及对心功能影响初探 |
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| 引用本文： | 杨玲玲,张钰哲,吴建新. 异丙肾上腺素复制大鼠心衰模型及对心功能影响初探[J]. 医学理论与实践, 2012, 25(10): 1141-1142 |
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| 作者姓名： | 杨玲玲 张钰哲 吴建新 |
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| 作者单位： | 大理学院基础医学院,云南省大理,671000 |
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| 摘 要： | 目的:探讨异丙肾上腺素制备大鼠心衰模型的方法及其对心功能的影响。方法:采用连续腹腔注射ISO制作大鼠慢性心衰模型,测定脏器指数、血流动力学指标及病理学观察。结果:模型组大鼠脏器指数、血流动力学指标及心脏病理学改变明显。结论:大鼠腹腔注射异丙基肾上腺素可有效建立大鼠慢性心衰模型。
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| 关 键 词： | 异丙肾上腺素 心力衰竭 |
Effect of XML Injection on Monocrotaline-induced Pulmonary Arterial Remodeling in Rats |
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| YANG Lingling , ZHANG Yuzhe , WU Jianxin. Effect of XML Injection on Monocrotaline-induced Pulmonary Arterial Remodeling in Rats[J]. The Journal of Medical Theory and Practice, 2012, 25(10): 1141-1142 |
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| Authors: | YANG Lingling ZHANG Yuzhe WU Jianxin |
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| Affiliation: | .Basal Medical College,Dali University,Dali,Yunnan Province 671000 |
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| Abstract: | Objective:To study the method of isoproterenol induced chronic heart failure and its effects to cardiac function.Methods:The rats were given isoproterenol by intraperitoneal injection to simulate chronic heart failure models.After 10 days,to measure the organ indices,haemodynamics and to observe pathologic identification.Results:Compared with control group,the organ indices,haemodynamics and pathologic identification of the model group showed significant differences.Conclusion:The method of isoproterenol induced chronic heart failure is efficient. |
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| Keywords: | Isoproterenol Heart failure |
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