两头尖提取物的抗炎镇痛作用初探

目的研究两头尖提取物的抗炎镇痛作用。方法采用二甲苯致小鼠耳肿胀实验、醋酸致小鼠腹腔毛细血管通透性增高实验、新鲜蛋清致大鼠足跖肿胀实验、大鼠棉球肉芽增生实验考察两头尖提取物的抗炎作用,用小鼠扭体实验考察其镇痛作用。结果实验表明,两头尖提取物对各种炎症模型均有显著的抑制作用,并能显著减少醋酸致小鼠扭体反应次数。结论两头尖提取物有良好的抗炎镇痛作用。

Study on Anti-inflammatory and Analgesic Actions of Extract of Anemone Raddeana Regel

Objective To study anti-inflammatory and analgesic actions of extract ofAnemone raddeana Regel(EAR).Method Anti-inflammatory action was observed by ear edema model in mice with dimethyl benzene,blood capillary permeability enhancement by acetic acid in mice,foot-swelling model induced by fresh albumen in rats and cotton gramuloma model in rats.Analgesic effect was tested by the method of writhes of mice.Results The experiments proved that the EAR had significant inhibition on every kind of inflammatory methods.It could also decrease the reaction to writhes in mice induced by acetic acid.Conclusion EAR has good anti-inflammatory and analgesic actions.