不孕症患者卵巢血流灌注与临床妊娠的研究

目的探讨不孕症患者在药物治疗过程中卵泡发育及卵巢血流灌注与临床妊娠的关系。方法应用经阴道彩色多普勒超声对88例药物治疗中的不孕症患者106个排卵周期的卵泡发育及卵巢血流灌注情况进行监测。结果106个排卵周期中29个周期妊娠，妊娠率27.36%，从卵泡发育到排卵期卵巢血流越来越丰富，RI及S/D值越来越低，血中E2水平逐渐升高，到排卵前舒张期血流呈高振幅低阻抗，此时卵泡直径最大，血E2水平上升达峰值，结果显示妊娠组的血流灌注及E2水平明显优于非妊娠组。结论不孕症患者治疗过程中卵泡发育与卵巢血流灌注及一定的E2水平对妊娠起着重要作用。

Study on ovarian perfusion and clinical pregnancy in patients with infertility

Objective： To study the relationship between the follicular development, the ovarian perfusion and the pregnancy of the infertile women being treated with medicine. Methods ： The follicular development and the ovarian perfusion of one hundred and six ovulation cycles in eighty - eight infertile women during treatment were monitored with transvaginal color ultrasound. Results ： Twenty - nine of one hundred and six women conceived and the pregnant rate was 27.36%. The ovarian perfusion became more and more abundant and coincident with the follicular development. However, in the ovulation period RI and S/D turned to low level, the blood E2 gradually increased. The diastolic flow waveforms has high amplitude with low impedance before ovulation, the diameters of the follicles were large, the blood E2 increased and attained the peak values. The result showed that the ovarian perfusion and the blood E2 of the conceived group were obviously better than those of the nonpregnant group respectively. Conclusions ： The follicular development and the ovarian perfusion and the degree blood E2 play vital role in the pregnancy of the infertile women during treatment with medicine.