| 亚砷酸治疗血液肿瘤的临床分析 |
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| 引用本文： | 严巨明,陈幸华,孔佩艳,魏立,刘红,王庆余.亚砷酸治疗血液肿瘤的临床分析[J].重庆医学,2003,32(10):1322-1323,1336. |
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| 作者姓名： | 严巨明 陈幸华 孔佩艳 魏立 刘红 王庆余 |
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| 作者单位： | 1. 宜宾第二人民医院血液科,644000
2. 第三军医大学新桥医院血液科,重庆,400037 |
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| 摘 要： | 目的：总结亚砷酸在造血系统恶性肿瘤治疗中的疗效。方法：分析亚砷酸在治疗2例复发难治性多发性骨髓瘤(MM)、2例骨髓增生异常综合征-RAEB(MDS-RAEB)、7例急性早幼粒细胞白血病(APL)、5例慢性粒细胞白血病急性变(CMLBC)患者的疗效及不良反应。结果：复发难治性多发性骨髓瘤患者1例进步，1例缓解；APL患者5例CR1，1例CR2，1例PR；CML-BP患者2例CR，2例PR，1例NR；2例MDS患者1例基本缓解，1例无效。全部病例治疗相关不良反应较轻。结论：用亚砷酸治疗造血系统恶性肿瘤疗效好，使用较安全；可作为治疗造血系统难治、复发性肿瘤的重要选择之一。
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| 关 键 词： | 亚砷酸 治疗 血液肿瘤 |
| 文章编号： | 1671-8348(2003)10-1322-03 |
Clinical analysis of the effect of arsenic trioxide on treating hematologic malignancy |
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| YAN Ju ming,CHEN Xing hua,KONG Pei yan ,et al..Clinical analysis of the effect of arsenic trioxide on treating hematologic malignancy[J].Chongqing Medical Journal,2003,32(10):1322-1323,1336. |
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| Authors: | YAN Ju ming CHEN Xing hua KONG Pei yan |
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| Institution: | YAN Ju ming,CHEN Xing hua,KONG Pei yan *,et al. |
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| Abstract: | Objective To discuss the effect of arsenic trioxide on treating hematologic malignancy. Methods Observed the treatment effects and side effects in 2 cases of relapsed MM,2 cases of MPS RAEB,7 cases of APL and 5 cases of CML BC. Results One case achieved progress and another obtained remission in relapsed MM, respectively, 5 CR1 and 1 PR2 and 1 NR in 7 APL, 2 CR and 2 PR and 1 NR in 5 CML BC cases, 1 CR and 1 NR in 2 MDS. There were mild side effects. Conclusion The relapsed cases are few in hematologic malignancy treated with arsenic trioxide;arsenic trioxide may precedently served as one effective medicine in treatment of relapsed hematologic malignancy. |
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| Keywords: | arsenic trioxide treatment hematologic malignant |
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