| 恶性间皮瘤的超微结构诊断和鉴别诊断 |
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| 引用本文： | 于国,李维华. 恶性间皮瘤的超微结构诊断和鉴别诊断[J]. 解放军医学杂志, 1988, 0(4) |
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| 作者姓名： | 于国 李维华 |
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| 作者单位： | 解放军总医院病理科(于国)，解放军总医院病理科(李维华) |
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| 摘 要： | 本研究结果表明:电镜下,恶性间皮瘤瘤细胞表面及其内腔表面均有细长蓬发样微绒毛,胞浆内有丰富的张力微丝。相反,转移性腺癌的微绒毛短小,胞浆内的张力微丝稀少或缺乏。转移性腺癌有微绒毛根、板层小体、糖萼小体、纤毛和粘液分泌颗粒,而恶性间皮瘤则缺乏这些表现。作者认为,当恶性间皮瘤和胸腹膜的转移癌鉴别诊断困难时,进行电镜观察是必要的。
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| 关 键 词： | 恶性间皮瘤 转移性腺癌微绒毛 粘液分泌颗粒 |
ULTRASTRUCTURAL DIAGNOSIS AND DIFFERENTIAL DIAGNOSIS OF MALIGNANT MESOTHELIOMA |
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| Yu Guo and Li Weihua. ULTRASTRUCTURAL DIAGNOSIS AND DIFFERENTIAL DIAGNOSIS OF MALIGNANT MESOTHELIOMA[J]. Medical Journal of Chinese People's Liberation Army, 1988, 0(4) |
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| Authors: | Yu Guo and Li Weihua |
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| Affiliation: | Yu Guo and Li Weihua. Department of Pathology,General Hospital of PLA. Beijing |
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| Abstract: | Our observations proved that malignant mesothelioma cells possessed slender and long bush-like microvilli on their surface and intracellular lumina, and, in addition, abundant tonofilaments were found in the cytoplasm, in contrast, microvilli were relatively short and sparse or tonofilaments were absent in the cytoplasm in metastatic adenocarcinoma. The latter was shown to have microvilious rootlets (17/20), lamellar bodies (6/20), glycocalyceal bodies (17/20), cilia (12/20) and mucinous secretory granules (18/20), which were absent in the malignant mesothelioma. Therefore, it is necessary to use electron microscopic technic to differentiate malignant mesothelioma from some confusing metaslatic carcinoma of pleura and peritoreum. |
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| Keywords: | Malignant mesothelioma Metastatic adenocarcmoma Microvilli Mucinous secretory granules |
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