| 自体软骨-软骨膜复合移植修复鼓膜 |
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| 引用本文： | 赵云峰,吴展元,潘维忠,陈芝胜. 自体软骨-软骨膜复合移植修复鼓膜[J]. 广东医学, 2000, 21(1): 16-17 |
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| 作者姓名： | 赵云峰 吴展元 潘维忠 陈芝胜 |
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| 作者单位： | 1. 广东省湛江中心人民医院耳鼻喉科,524037
2. 湖北医科大学附属第一医院耳鼻喉科,430060 |
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| 摘 要： | 目的 探讨自体软骨－软骨膜复合移植修复鼓膜的组织学转归及其在中估手术的应用前景。方法 将１６只家兔双耳正常切除后，用其自体耳廓软－软骨膜修复。并对术后不同时期移植物行组织学、扫描电镜、透射电镜观察。结果 术后１个月移植物已开始修，术后３个月移植物细胞形态、组织结构基本恢复正常，术后５个月修复完成，移植物鼓室面 耳道面分别被覆光滑的单层立方上皮及复层鳞状上皮。结论 自体软骨一软骨膜是一种有前任的中耳
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| 关 键 词： | 复合自体移植 软骨－软骨膜 鼓室成形术 |
| 修稿时间： | 1999-07-23 |
Experimental study on using composite cartilage-perichondrial autograft for tympanoplasty in rabbits |
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| Zhao Yunfeng,Wu Zhanyuan,Pan Weizhong,et al.. Experimental study on using composite cartilage-perichondrial autograft for tympanoplasty in rabbits[J]. Guangdong Medical Journal, 2000, 21(1): 16-17 |
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| Authors: | Zhao Yunfeng Wu Zhanyuan Pan Weizhong et al. |
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| Affiliation: | Zhao Yunfeng,Wu Zhanyuan,Pan Weizhong,et al. Department of Otolaryngology,Zhanjiang Central Hospital,Zhanjiang 524037 |
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| Abstract: | Objective To study the histological fate and clinical prospect of composite cartilage-perichondrial autograft (CCPA) in tympanoplasty.Methods Experimental tympanoplasty by using CCPA was carried out in 16 rabbits. Results Grafts were found adherent to the recipient site 1 month after operation.Histological staining with H-E revealed some abnormal chondrocytes within the lacunae, but there were cellular division and epithelization on both surfaces of the grafts. Morphology of chondrocytes and simple epithelium was nearly normal 3 months after operation. By the 5th month, chondrocytes were normal and graft edges healed completely without scar tissue formation. The medial surface was covered with simple cuboidal epithelium and the outer surface covered with squamous epithelium.Conclusion CCPA has a good prospect in tympanoplasty |
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| Keywords: | Composite autograft Cartilage-perichondrial Tympanoplasty |
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