优化选择当归补血汤的煎煮方法

目的:对当归补血汤几种煎药方法进行比较研究,优选煎药条件和方法。方法:采用正交试验设计和高效液相色谱法,以当归补血汤中的黄芪甲苷含量为指标,考察不同煎煮时间、煎煮次数、煎煮方法下的药物含量。结果:经直观分析确定的最优煎药方案为自动煎药机,煎煮时间40min,煎煮次数1次。结论:传统的直火加热法无法将当归补血汤中的有效成分最大限度地提取出来,发挥最大疗效,应该被现代的自动煎药包装机所取代。

Optimization design of decocting the TCM formula Danggui Buxue Tang

OBJECTIVE To compare the decoction methods for TCM formula Danggui Buxue Tang and to select one the best.METHODS Using orthogonal experiment design and High Performance Liquid Chromatography(HPLC), the content of astragaloside IV in the juices was prepared by different decoction methods and operation factors,including time and counts.RESULTS It was shown by direct analysis that using auto-decoction machine in 40 minutes only once was the best method.CONCLUSION The effective content of Danggui BuxueTang couldn't be extracted maximum by the traditional method of direct-heating.Using auto-decoction machine as a substitute for direct-heating method should be a tendency.