人工肝支持系统治疗慢性重型肝炎有关并发症的防治研究

目的探讨人工肝支持系统(ALSS)治疗慢性重型肝炎时并发症的发生及其防治措施.方法分析人工肝支持系统对159例慢性重型肝炎310次治疗中出现的78次并发症资料,探讨各种并发症的发生及影响因素.结果并发症发生率25.2%(78/310),其中血浆过敏反应最多见,占18.1%(56/310),跨膜压增高次之,占4.5%(14/310),最严重的并发症是低血压0.97%(3/310).结论 ALSS对慢性重型肝炎的治疗是较为安全有效的,积极防治并发症是提高治疗成功率的关键措施之一.

Clinical study of artificial liver support system complications on treating chronic severe hepatitis

Objective To study the complication of artificial liver support system(ALSS) on treating patients with chronic severe hepatitis.Methods The complications of 159 chronic severe hepapatients who received 310 times ALSS therapy were investigated.Results During the process of treatments,78 times of side effects were found(25.2%).Most of them was plasma allergy (18.1%),the second was intractable transmembrane pressure increase(4.5%).The most severe complication was hypotension(0.97%).Of all patients,most were relieved after treatment.Conclusions Artificial liver support system has been proved to be safe and effective in treating chronic severe hepatitis, prevent and treat the complications actively are the most important measure to obtain success.