| 苦菜体内外抗氧化作用的实验研究 |
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| 引用本文： | 卢新华,谷彬,刘思妤,王俊杰,陈钢. 苦菜体内外抗氧化作用的实验研究[J]. 右江医学, 2007, 35(2): 120-122 |
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| 作者姓名： | 卢新华 谷彬 刘思妤 王俊杰 陈钢 |
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| 作者单位： | 1. 湘南学院基础医学部,湖南郴州,423000
2. 中南大学湘雅医学院,湖南长沙,410078 |
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| 摘 要： | 目的观察苦菜(PV)的抗氧化作用。方法采用TBA法、NBT法测定小鼠心、肝、脑、肾组织中丙二醛(MDA)含量和超氧化物歧化酶(SOD)活性。结果苦菜能降低心、脑、肝、肾体外组织中MDA的含量,苦菜3种剂量均有显著降低小鼠体内心、肝、脑、肾组织中MDA含量(P<0.05或<0.01);BVE 250 mg、500 mg/(kg.d),能显著提高上述组织中SOD活性(P<0.05或<0.01)。结论苦菜具有明显的体内外抗氧化作用。
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| 关 键 词： | 苦菜 丙二醛 超氧化物歧化酶 抗氧化 |
| 文章编号： | 1003-1383（2007）02-0120-03 |
| 收稿时间： | 2006-12-05 |
| 修稿时间： | 2007-03-28 |
Experimental Research on the antioxygenation of Patrinia Villosaon in vitro and vivo |
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| LU Xin-hua,GU Bin,LIU Si-yu,WANG Jun-jie,CHEN Gang. Experimental Research on the antioxygenation of Patrinia Villosaon in vitro and vivo[J]. Youjiang Medical Journal, 2007, 35(2): 120-122 |
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| Authors: | LU Xin-hua GU Bin LIU Si-yu WANG Jun-jie CHEN Gang |
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| Abstract: | Objective To study the antioxygenation of Patrinia Villosaon(PV).Methods Content of maiondialdehyde(MDA),superoxide dismutase(SOD)in the heart,brain,liver and kidney of rat and mice were measured by TBA and NBT technique respectively.Results Patrinia Villosaon could decrease the content of MDA of liver,heart,kidney,brain homogenate in vitro.PV could decrease evidently content of MDA in all tissue in vivo(P<0.05or0.01),250 mg and 500 mg/(kg·d),and could increase significantly the activity of SOD.Conclusion PV has antioxygenation effect obviously in vitro and vivo of rat. |
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| Keywords: | patrinia villosaon(PV) MDA SOD antioxygenation |
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