| 采用高效液相色谱法同时测定复方丹参滴丸中的多成分含量 |
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| 引用本文： | 姚琳,程维明.采用高效液相色谱法同时测定复方丹参滴丸中的多成分含量[J].上海医药,2011,32(8):413-415. |
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| 作者姓名： | 姚琳 程维明 |
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| 作者单位： | 1. 上海市食品药品包装材料测试所,上海,201203
2. 浙江省食品药品检验所,杭州,310004 |
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| 摘 要： | 目的:采用高效液相色谱法(HPLC法)同时测定复方丹参滴丸中的7种成分.方法:应用Diamonsil C18色谱柱,以乙腈-甲醇-0.1%磷酸溶液为流动相进行梯度洗脱,在柱温35 ℃下使用205、270和285 nm三波长同时检测.结果:7种成分的峰面积与浓度的线性关系良好,平均回收率在94.3%～101.3%间,加样...
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| 关 键 词： | 复方丹参滴丸 HPLC法 含量测定 |
Quantitative determination of multi-components in Compound Danshen Dripping Pill by HPLC method |
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| YAO Lin,CHENG Wei-ming.Quantitative determination of multi-components in Compound Danshen Dripping Pill by HPLC method[J].Shanghai Medical & Pharmaceutical Journal,2011,32(8):413-415. |
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| Authors: | YAO Lin CHENG Wei-ming |
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| Institution: | YAO Lin1*,CHENG Wei-ming2**(1.Shanghai Food and Drug Packaging Material Control Center,Shanghai,201203,2.Zhejiang Institute for Food and Drug Control,Hangzhou,310004) |
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| Abstract: | Objective: To establish an HPLC method for the simultaneous determination of 7 components in Compound Danshen Dripping Pill.Method: Diamonsil C18 was used as the solid phase,and acetonitrile-methanol-0.1%(v/v) phosphoric acid as the mobile phase for the gradient elution.The column temperature was 35℃,and the detective wavelengths were set as 205,270 and 285 nm.Results: the linearities of the 7 components were all good in the range of the test concentration,and the average recoveries were between 94.3% and 101.3%.Conclusion: the method was simple,reliable and reproducible,which could be used as quality control for the determination of Compound Danshen Dripping Pill. |
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| Keywords: | Compound Danshen Dripping Pill HPLC content determination |
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