| CEA、CA50、CA19-9和CA125联合检测在肿瘤性梗阻性黄疸诊断中的意义 |
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| 引用本文： | 陈圣开,何世举.CEA、CA50、CA19-9和CA125联合检测在肿瘤性梗阻性黄疸诊断中的意义[J].重庆医科大学学报,2011,36(7). |
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| 作者姓名： | 陈圣开 何世举 |
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| 作者单位： | 重庆市第三人民医院肝胆外科; |
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| 摘 要： | 目的:探讨肿瘤标志物CEA、CA50、CA19-9和CA125联合检测在肿瘤性梗阻性黄疸诊断中的意义。方法:分析我科2004年1月-2011年1月151例梗阻性黄疸患者的有关临床资料。资料分为肿瘤组(74例)和良性疾病组(77例)。结果:CEA和CA125检测值在肿瘤组明显高于良性疾病组(P<0.05)。CEA、CA50、CA19-9和CA125在肿瘤组的敏感性分别为:27.40%、62.86%、59.46%和21.43%,与良性疾病组比较差异无统计学意义(P>0.05)。CEA大于参考值上限2倍的敏感性在肿瘤组明显高于良性疾病组,分别为13.70%和2.60%(P<0.05)。CEA、CA50、CA19-9 3项联合检测同时2项以上异常的敏感性在肿瘤组明显高于良性疾病组,分别为57.97%和40.54%(P<0.05),特异性59.46%,准确性58.74%,阳性预测值57.14%,阳性似然比1.43。CEA、CA50、CA19-9和CA125 4项联合检测同时3项以上异常的敏感性在肿瘤组明显高于良性疾病组,分别为34.14%和5.88%(P<0.05),特异性94.12%,准确性61.33%,阳性预测值8...
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| 关 键 词： | 肿瘤标志物 CEA CA50 CA19-9 CA125 梗阻性黄疸 诊断 |
The diagnostic significance of the combined detection of serum CEA,CA50,CA19-9 and CA125 in patients with obstructive jaundice from tumors |
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| CHEN Sheng-kai,HE Shi-ju.The diagnostic significance of the combined detection of serum CEA,CA50,CA19-9 and CA125 in patients with obstructive jaundice from tumors[J].Journal of Chongqing Medical University,2011,36(7). |
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| Authors: | CHEN Sheng-kai HE Shi-ju |
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| Institution: | CHEN Sheng-kai,HE Shi-ju(Department of Hepatobiliary Surgery,the Third People's Hospital of Chongqing) |
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| Abstract: | |
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| Keywords: | tumor marker CEA CA50 CA19-9 CA125 obstructive jaundice diagnosis |
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