常规细胞形态学检查对浆膜腔积液的鉴别诊断价值

目的探讨恶性浆膜腔积液病因及常规细胞形态学检查对恶性积液的诊断性能。方法对2002-01～2006-12的2801例浆膜腔积液原因待查患者标本的常规细胞形态学检查结果进行分析。标本首先进行颜色、透明度、Rivalta试验及细胞计数常规检查,然后离心、涂片,采用瑞吉染色进行细胞分类和形态观察。结果浆膜腔积液常规细胞形态学检查结果对恶性积液的检验诊断灵敏度75.2%,诊断特异性99.8%,实验结果的阳性预期值99.3%,实验结果的阴性预期值91.7%,实验总有效率93.2%。结论浆膜腔积液常规细胞形态学检查对良、恶性积液的鉴别诊断有很高的特异性和良好的灵敏度,适合普遍推广应用。

The differential diagnosing value of cytomorphologic routine examination for unknown origin serous effusions

Objective To discuss clinical diagnosis value of cytomorphologic routine examination for serous effusions.Method The color,diaphaneity and Rivalta test of serous effusions were examined in 2 801 patients. Then different cell count and morphologic analysis were made after cells preparetion by centrifuge,smear and Wright's and Gimsa's stain.Results The diagnosis efficiency for malignant effusions was that: diagnosis sensitivity (75.2%), specificity (99.8%), positive expectant value of experimental results (99.3%), negative expectant value of experimental results (91.7%) and total effective rate of experimental results (93.2%). Conclusion The routine cytomorphology examination for unknown origin serous effusions has good diagnostic value, specially in specificity and sensitivity for differential diagnosis between benign effusions and malignant effusions. So it is suitably applied to make publicity.