| 依达拉奉对急性脑梗死患者血清NSE、MDA表达的影响 |
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| 引用本文： | 孟文格,陈小贺,陈欣华,陈浩,冯彦平,王生池. 依达拉奉对急性脑梗死患者血清NSE、MDA表达的影响[J]. 山东医药, 2008, 48(37): 9-11 |
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| 作者姓名： | 孟文格 陈小贺 陈欣华 陈浩 冯彦平 王生池 |
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| 作者单位： | 石家庄市第一医院,河北,石家庄,050011;石家庄市中医院,河北,石家庄,050011 |
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| 摘 要： | 目的 研究依达拉奉对急性脑梗死患者血清神经元特异性烯醇化酶(NSE)、丙二醛(MDA)表达的影响.方法 将120例急性脑梗死患者随机分为对照组和依达拉奉组,对照组给予常规治疗,依达拉奉组在常规治疗基础上给予依达拉奉30 mg 生理盐水100 ml静滴,2次/d,连续14 d.检测治疗前后血清中NSE、MDA的变化.结果 依达拉奉组治疗后血清NSE、MDA明显减少,发病72 h和治疗后7、14 d均明显低于对照组(P＜0.05).结论 依达拉奉可以减轻急性脑梗死患者脑细胞的损害.
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| 关 键 词： | 脑梗死 依达拉奉 特异性烯醇化酶 丙二醛 |
Effect of Edaravone on the serum levels of NSE,MDA in patients with acute cerebral infarction |
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| MENG Wen-ge,CHEN Xiao-he,CHEN Xin-hua,CHEN Hao,FENG Yan-ping,WANG Sheng-chi. Effect of Edaravone on the serum levels of NSE,MDA in patients with acute cerebral infarction[J]. Shandong Medical Journal, 2008, 48(37): 9-11 |
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| Authors: | MENG Wen-ge CHEN Xiao-he CHEN Xin-hua CHEN Hao FENG Yan-ping WANG Sheng-chi |
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| Affiliation: | MENG Wen-ge1,CHEN Xiao-he,CHEN Xin-hua,CHEN Hao,FENG Yan-ping,WANG Sheng-chi(1 Shijiazhuang No.1 Hospital,Shijiazhuang 050011,P.R.China) |
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| Abstract: | Objective To study the influence of Edaravone on serum neuron-specific enolase(NSE) and malondialdehyde(MDA) level in patients with acute cerebral infarction.Methods 120 patients with acute cerebral infarction were randomly divided into control group of 60 cases and Edaravone group of 60 cases.The control group was treated routinely.Besides routine tharapy the Edaravone group were treated by Edaravone of 30 mg,twice a day,total of 14 day.The serum levels of NSE and MDA were investigated before and after tre... |
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| Keywords: | cerebral infarction Edaravone superoxide dismutase malondialdehyde |
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