| 三七叶提取物对大鼠脑缺血模型的影响 |
| |
| 引用本文： | 孙晓波,徐惠波,纪凤兰,温富春,丁涛,张伟,张殿文.三七叶提取物对大鼠脑缺血模型的影响[J].中药药理与临床,2004,20(2):17-18. |
| |
| 作者姓名： | 孙晓波 徐惠波 纪凤兰 温富春 丁涛 张伟 张殿文 |
| |
| 作者单位： | 吉林省中医中药研究院,长春,130021 |
| |
| 摘 要： | 目的:观察三七叶提取物对大鼠大脑中动脉缺血模型的影响.方法:通过栓线法造成大脑中动脉缺血,观察三七叶提取物对缺血大鼠的行为状态、脑缺血面积、脑组织形态学的作用.结果:三七叶提取物42.0、21.0、10.5mg/kg能明显改善大鼠脑缺血后的行为状态,缩小缺血范围,降低缺血程度,使病变的脑组织得到明显的改善.
|
| 关 键 词： | 三七叶提取物 总皂苷 总黄酮 脑缺血 |
Effect of Panax pseudo-ginseng leaves extract (PPGLE) on the cerebral ischemia injury model of rat |
| |
| Sun Xiaobo,Xu Huibo,Ji Fenglan,Wen Fuchun,Ding Tao,Zhang Wei,Zhang Dianwen.Effect of Panax pseudo-ginseng leaves extract (PPGLE) on the cerebral ischemia injury model of rat[J].Pharmacology and Clinics of Chinese Materia Medica,2004,20(2):17-18. |
| |
| Authors: | Sun Xiaobo Xu Huibo Ji Fenglan Wen Fuchun Ding Tao Zhang Wei Zhang Dianwen |
| |
| Abstract: | Objective: To study the protective effect of PPGLE on the cerebral ischemia injury. Method: Employ focal cerebral ischemia model via the thread occluding method to explore the protective effects of PPGLE on the score of neurological deficits, the rate of cerebral infarction and histomorphology of cerebral ischemia rats. Results: PPGLE was perfusied to the stomach of rats by 42.0, 21.0 and 10.5mg/kg respectively, which could distinctly improve the score of neurological deficits of cerebral ischemia rats and reduce the rates of cerebral infarction rats and the level of cerebral ischmia injury. It is also able to improve the cerebral textus of pathological change. |
| |
| Keywords: | Panax Pseudo ginseng leaves extract total saponin total flavone focal cerebral ischemia |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
