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多巴反应性肌张力障碍10例分析
引用本文:夏彬,朱宁,赵伟丽,刘合玉. 多巴反应性肌张力障碍10例分析[J]. 中国实用神经疾病杂志, 2010, 13(1): 28-30
作者姓名:夏彬  朱宁  赵伟丽  刘合玉
作者单位:郑州大学第二附属医院神经康复科,郑州,450014;郑州大学第二附属医院神经康复科,郑州,450014;郑州大学第二附属医院神经康复科,郑州,450014;郑州大学第二附属医院神经康复科,郑州,450014
摘    要:目的认识多巴反应性肌张力障碍的临床特征,以期早期诊治,并加深对该病的认识。方法对10例DRD患者进行临床分析。结果10例患者,男3例,女7例,发病年龄4~28岁,平均12岁,首发症状均为肌张力障碍,下肢起病者8例,上肢起病2例,全部病人均有晨轻暮重的现象,给予美多巴62.5~125mg/d治疗有显著疗效。结论DRD是一种较为罕见的遗传性运动障碍疾病,小剂量多巴制剂有显著、持续疗效,早期治疗效果好,需与其他肌张力障碍相鉴别。

关 键 词:肌张力障碍  左旋多巴  美多巴

Analysis of 10 cases of dopa-responsive dystonia
Xia Bin,Zhu Ning,Zhao Weili,et al. Analysis of 10 cases of dopa-responsive dystonia[J]. Chinese Journal of Practical Neruous Diseases, 2010, 13(1): 28-30
Authors:Xia Bin  Zhu Ning  Zhao Weili  et al
Affiliation:Xia Bin,Zhu Ning,Zhao Weili,et al.Department of Neurological Rehabilitation,Second Affiliated Hospital of Zhengzhou University,Zhengzhou 450014,China
Abstract:Objective To understand the multi-dopa-responsive dystonia clinical features,with a view to early diagnosis and treatment as well as to enhance awareness of the disease.Methods Ten cases of patients with DRD were analyzed.Results Ten patients,three cases of men and 7 cases of women,onset age 4 ~ 28 years old,average age 12 years old,the first symptoms were dystonia,onset of lower extremity in 8 cases,2 cases of upper limb onset,all patients with morning light weight were the phenomenon of the morning,Madopa...
Keywords:Dystonia  L-dopa  Madopar  
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