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Sleep Problems and Life Satisfaction as Predictors of Health in Men with Sex Chromosome Aneuploidies
Authors:Krister W. Fjermestad  Simen Stokke
Affiliation:1. Frambu Resource Centre for Rare Disorders;2. University of Oslo
Abstract:More knowledge is needed about men with sex chromosome aneuploidies (SCA). We present self-reported data from 53 men with SCA (Mage = 36.8 years, SD = 12.3, range 19–67). The Health Survey–Short Form (SF-36) measured eight health domains (physical functioning, role-physical, role-emotional, vitality, emotional health, social functioning, pain, general health). The Pittsburgh Sleep Quality Index measured sleep problems. The Personal Wellbeing Index measured satisfaction with eight life domains. Compared to norms, SCA reported poorer health (mean d = ?0.80) and more sleep problems (mean d = ?0.85). Differences between SCA and norms on personal well-being were small, except lower health satisfaction in SCA (d = ?1.06). Seven of eight regression models predicting the SF-36 domains from life satisfaction and sleep problems were significant (explained variance 12.2% to 46.2%), except physical functioning (ns). Clinical assessment/intervention for a broad range of health and sleep problems is indicated for men with SCA.
Keywords:47XXY  47XYY  Klinefelter syndrome  male health  sex chromosome aneuploidy
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