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Complications of Uveitis: The Northern California Epidemiology of Uveitis Study |
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| Authors: | David C. Gritz Eric J. Schwaber Ira G. Wong |
| Affiliation: | 1. Francis I. Proctor Foundation for Research in Ophthalmology, San Francisco, California, USA;2. University of California, San Francisco, Department of Ophthalmology, Koret Vision Research Center, San Francisco, California, USA;3. The Permanente Medical Group, Kaiser Permanente Oakland Medical Center, Oakland, California, USA;4. Kaiser Permanente Richmond Medical Center, Richmond, California, USA;5. Tufts University School of Medicine, Boston, Massachusetts, USA;6. Stanford University, Department of Ophthalmology, Stanford, California, USA |
| Abstract: | Purpose: To describe the uveitis complications in a large, community-based cohort. Methods: Retrospective, community-based, cross-sectional cohort study analyzing complications and associations with complications. Results: A total of 844 cases of uveitis were found; 342 were new-onset, and 462 were prior-onset. In total, 29.5% of patients were affected by one or more complications associated with age, gender, course, and anatomic location of uveitis. Visual loss was experienced by 19.1% of patients and was associated with age, course of disease, and anatomic location of uveitis. Of the patients who developed glaucoma or elevated intraocular pressure over 30 mmHg, 3.9% (n = 33) were related solely to uveitis; 5.2% (n = 44) had an unclear or combined mechanism; and 1.8% (n = 15) were related solely to steroid response. Cystoid macular edema was associated with course of disease and anatomic location of uveitis. Conclusions: Complications affect a significant portion of uveitis patients, and are often associated with demographic and clinical factors. |
| Keywords: | Complications epidemiology glaucoma steroid-response uveitis |