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Contrast-enhanced magnetisation transfer MRI in metastatic lesions of the brain |
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| Authors: | P. Peretti-Viton D. Taieb J. M. Viton A. Flori X. Muracciole V. Benguigui G. Salamon |
| Affiliation: | Department of Neuroradiology, H?pital de la Timone, Boulevard Jean Moulin, F-13385 Marseille Cedex 5, France, FR Department of Physical Medicine and Rehabilitation, 92, rue Aguste Blanqui, F-13005 Marseille, France, FR Medical Informatics Department, H?pital Nord, Chemin des Bourrély, F-13015 Marseille, France, FR Department of Radiation Oncology, H?pital de la Timone, Boulevard Jean Moulin, F-13385 Marseille Cedex 5, France, FR |
| Abstract: | Our purpose was to compare prospectively the sensitivity of contrast-enhanced magnetisation transfer (MT) MRI and gradient-echo (GE) T1-weighted images in metastatic disease of the brain. We studied 52 patients with brain metastases, using conventional T1-weighted GE and MT spin-echo (SE) images after the same standard dose of gadolinium. Axial 5-mm reconstructions of GE data were compared with 5-mm MT images in the same plane. Metastases were counted independently by two neuroradiologists. In 12 patients (23 %) MT imaging showed more metastases than GE images (P = 0.03). We detected 68 more metastases with the former technique. Received: 27 July 1997 Accepted: 22 April 1998 |
| Keywords: | Brain metastases Magnetic resonance imaging Magnetisation transfer Contrast enhancement |
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