Impact of brain tumour treatment on quality of life |
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| Authors: | Heimans Jan J Taphoorn Martin J B |
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| Institution: | (1) VU Medical Centre Department of Neurology P. O. Box 7057 1007 MB Amsterdam, The Netherlands Tel.: +31-20/4442821 Fax: +31-20/4442800 E-Mail: jj.heimans@vumc.nl, NL;(2) University Medical Centre Utrecht Department of Neurology G03.228 P. O. Box 85500 3508 GA Utrecht, The Netherlands Tel.: +31-30/2507939 Fax: +31-30/2542100 E-Mail: m.j.b.taphoorn@neuro-azu.nl, NL |
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| Abstract: | Measurement of Health Related Quality of Life (HRQL) in brain tumour patients is important because brain tumours and brain
tumour treatment usually affect physical, cognitive as well as emotional functioning. Measurement of HRQL is important for
the understanding of disease burden and for the impact of specific tumour treatment. Quality of Life is a multidimensional
concept consisting of physical, psychological and social phenomena. A large number of Quality of Life instruments have been
developed. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and
the MOS Short-Form Health Survey are two frequently used general HRQL instruments. A specific brain tumour scale is the Brain
Cancer Module, which is designed to be used in combination with general questionnaires.
HRQL measurement and neuropsychological examination were used to investigate the impact of radiotherapy and surgery in low-grade
glioma patients and the influence of tumour volume, tumour localization, performance status and age in both low-grade and
high-grade glioma patients.
Received: 10 April 2002 Accepted: 16 April 2002 |
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| Keywords: | primary brain tumour glioma quality of life cognitive function |
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