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Age, an independent risk factor for thrombosis. Epidemiologic data
Authors:Mahé I  Caulin C  Bergmann J F
Affiliation:1. Department of Internal Medicine, Taichung Hospital, Ministry of Health and Welfare, Taichung, Taiwan;2. Department of Healthcare Administration, Central Taiwan University of Science and Technology, Taichung, Taiwan;3. Department of Health Services Administration, China Medical University, Taichung, Taiwan;4. Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan;5. Department of Public Health, China Medical University, Taichung, Taiwan;6. Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan;7. Graduate Institute of Clinical Medical Science and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan;8. Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan;1. Department of Haematology, Aalborg University Hospital, Aalborg, Denmark;2. Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark;3. Department of Cardiology, Center for Cardiovascular Research, Aalborg University Hospital, Aalborg, Denmark;4. Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark;5. Department of Clinical Biochemistry, Center for Cardiovascular Research, Aalborg University Hospital, Aalborg, Denmark
Abstract:The incidence of thrombosis--arterial and venous--increases with age. This is the case for atheromatous diseases, atrial fibrillation and even venous thromboembolic disease. Ischemic heart disease is the most common cause of death in the elderly. Atrial fibrillation, an independent risk factor for cerebral vascular accidents, affects around 10% of persons older than 80 years. The incidence of venous thromboembolic disease increases with age, reaching 12.5 per 1000 people older than 75 years, compared with 5 per 1000 aged 60-75 and 2.5 per 1000 aged 40-59. Elderly persons often have two or more cardiovascular or venous thromboembolic risk factors and thus a still higher risk of thrombotic events. Their risk of thrombosis justifies the systematic search for acquired risk factors to assess the level of risk and take appropriate prevention measures.
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