米索前列醇与米非司酮联合治疗稽留流产的疗效观察

目的 探讨米索前列醇与米非司酮联合治疗稽留流产的疗效.方法 选择我院收治的稽留流产患者120例,平均分为研究组与对照组.对照组患者给予口服乙烯雌酚,连服5d,第6d进行刮宫处理.研究组给予口服米非司酮,连服2d,第3d在阴道后穹窿处放置米索前列醇,待孕产物自然排出或阴道出血量高于100 ml时,进行刮宫处理.结果 研究组孕产物自然排出率明显高于对照组,P＜0.05;研究组手术时间、术中出血量及人工流产综合征发生率及再次清宫率均低于对照组,P ＜0.05或P＜0.01.结论 米索前列醇与米非司酮联合治疗稽留流产效果显著,具有成功率高、不良反应少、再次刮宫率低等优点,值得临床推广应用.

Misoprostol treatment of missed abortion with Mifepristone and Efficacy

Objective To investigate misoprostol missed abortion with mifepristone treatment efficacy. Methods Missed abortion in our hospital 120 patients were divided into study group and control group. The control group were treated with oral diethylstilbestrol, even 5d, 6d for the first curettage treatment. Study group received oral mifepristone and mifepristone, even 2d, 3d in the first misoprostol vaginal fornix, to be the product of natural progesterone vaginal bleeding or discharge was higher than 100mL for curettage treatment. Results The study group product of natural progesterone excretion rate was significantly higher （P 〈 0.05 ） ; study group operative time, blood loss and induced abortion syndrome incidence and re-curettage were lower than the control group （P 〈0.05 or P 〈 O. O1 ）. Conclusions Misoprostol missed abortion with mifepristone treatment effect is significant, with a high success rate, fewer adverse reactions, again curettage rate, worthy of clinical application.