四川省西昌市静脉吸毒人群丙型肝炎病毒感染情况研究

目的：了解四川省西昌市静脉吸毒人群丙型肝炎病毒（HCV）感染情况及其影响因素。方法l于2005年10月至11月在西昌市对静脉吸毒人群进行问卷调查，调查内容包括社会人口学、毒品使用、共用注射器具静脉吸毒以及性行为情况等，同时采集血样进行HCV抗体检测。结果：在招募的325名静脉吸毒者中，HCV感染率为61．8％（201／325）。多因素Logistic回归模型分析结果显示，无业（OR，1．90；95％CI，1．11．3．24）、近3个月共用针头或注射器（OR，2．40；95％CI，1．164．99）以及近6个月以性交为条件接受性伴提供的钱物、毒品或住处（OR，8．96；95％CI，1．15-69．58）与静脉吸毒人群HCV感染的关系有统计学意义。结论：四川省西昌市静脉吸毒人群中HCV感染率仍在升高，应该在该地区进一步加大干预工作的力度以控制HCV的传播。

HCV Prevalence and Associated Risk Factors among Injection Drug Users in Xichang County of Sichuan Province

Objective: To study HCV prevalence and factors associated with HCV infection among injection drug users (IDUs) in Xichang County of Sichuan Province. Methods: During October 2005 and November 2005, IDUs were investigated to collect socio-demographics, behavioral characteristics of drug use, sharing injection equipments and sexual practices in Xichang County, and blood specimens were also collected to test for antibodies against HCV. Results: Of the 325 IDUs, HCV prevalence was 61.8% (201/325). Multiple logistic regression model demonstrated that no employment (OR, 1.90; 95% CI, 1.11-3.24), sharing injector or syringe needle in the past 3 months (OR, 2.40; 95% CI, 1.16-4.99) and selling sex to male sex partner(s) in past 6 months (OR, 8.96; 95% CI, 1.15-69.58) were significantly associated with HCV infection among IDUs. Conclusion: HCV prevalence remains on the rise among IDUs in Xichang County of Sichuan Province, and intervention to IDUs should be strengthened to control HCV transmission in this area.