| 三维多普勒血流频谱定量技术评估2型糖尿病患者拇指动脉血流 |
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| 引用本文： | 张韬,夏良华,赵峰,王洪兴,李幼子,陈明. 三维多普勒血流频谱定量技术评估2型糖尿病患者拇指动脉血流[J]. 中国医学影像技术, 2016, 32(6): 876-880 |
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| 作者姓名： | 张韬 夏良华 赵峰 王洪兴 李幼子 陈明 |
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| 作者单位： | 上海市浦东新区惠南镇社区卫生服务中心, 上海 201301,同济大学医学院附属东方医院医学超声科, 上海 200120,上海市浦东新区光明中医医院超声科, 上海 201300,上海市浦东新区惠南镇社区卫生服务中心, 上海 201301,上海市浦东新区惠南镇社区卫生服务中心, 上海 201301,同济大学医学院附属东方医院医学超声科, 上海 200120 |
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| 基金项目： | 上海市卫生局科研项目(20134138);上海市浦东新区卫生系统重点学科群建设资助(PWZxq2014-01)。 |
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| 摘 要： | 目的 应用三维多普勒频谱定量分析技术检测2型糖尿病(T2DM)患者拇指动脉血流,评估T2DM患者外周微小动脉血流的特点。方法 本研究根据T2DM的病程,将所有患者分为T2DM组1(病程≤5年;n=47)与组2(病程>5年;n=45)两组,46例正常志愿者为对照组。应用三维多普勒频谱定量分析技术的流速-血管深度频谱图模式,测定拇指动脉内径及拇指动脉频谱图收缩期瞬时最大血流面积(Aflow)。并且测定收缩期最大血流速度(PSV)、舒张末期血流速度(EDV)、阻力指数(RI)。结果 所有T2DM患者拇指动脉血管内径均较对照组缩小[正常人拇指动脉血管内径平均为(2.11± 0.19)mm,T2DM组1平均为(1.71±0.21)mm,T2DM组2平均为(1.59± 0.25)mm,P<0.001];T2DM两组患者的拇指动脉Aflow较对照组显著减低[T2DM组1平均为(61.35±10.66)mm2/s,T2DM组2平均为(46.50±6.59)mm2/s,对照组平均为(75.32±11.97)mm2/s,P<0.001]。而且T2DM组2的拇指动脉Aflow较T2DM组1更为减低(P<0.001)。结论 三维多普勒超声技术所测拇指动脉内径与相关血流参数,可应用于临床观测T2DM患者外周微小血管的损伤度,为观测糖尿病患者外周血管病变提供一种可靠的无创伤性分析手段。
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| 关 键 词： | 糖尿病,2型 小动脉 超声检查 |
| 收稿时间： | 2015-11-02 |
| 修稿时间： | 2016-02-01 |
Evaluation of blood flow in finger arterioles in patients with type 2 diabetes by quantitative three-dimensional Doppler spectrum |
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| ZHANG Tao,XIA Lianghu,ZHAO Feng,WANG Hongxing,LI Youzi and CHEN Ming. Evaluation of blood flow in finger arterioles in patients with type 2 diabetes by quantitative three-dimensional Doppler spectrum[J]. Chinese Journal of Medical Imaging Technology, 2016, 32(6): 876-880 |
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| Authors: | ZHANG Tao XIA Lianghu ZHAO Feng WANG Hongxing LI Youzi CHEN Ming |
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| Affiliation: | Community Health Service Center, Huinan Town Pudong New District, Shanghai 201301, China,Department of Ultrasound, Shanghai East Hospital, Tongji Medical School, Tongji University, Shanghai 200120, China,Division of Ultrasound, Shanghai Pudong Guang-ming Chinese Medicine Hospital, Shanghai 201300, China,Community Health Service Center, Huinan Town Pudong New District, Shanghai 201301, China,Community Health Service Center, Huinan Town Pudong New District, Shanghai 201301, China and Department of Ultrasound, Shanghai East Hospital, Tongji Medical School, Tongji University, Shanghai 200120, China |
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| Abstract: | Objective To evaluate changes in peripheral arterioles in patients with type 2 diabetes (T2DM) in vivo with quantitative three-dimensional Doppler spectrum on measurement of artery flow at the tip of the right finger. Methods All of the 92 patients with T2DM were divided into two subgroups as T2DM group 1(n=47) and T2DM group 2(n=45) according to the disease progress. Forty-six healthy subjects were selected as control group. Diameter of finger arterioles at right thumb, maximal area of instantaneous flow in finger arterioles from the flow spectrum (Aflow), peak systolic velocity (PSV), end diastolic velocity (EDV) and resistance index (RI) were calculated from the quantitative three-dimensional Doppler spectrum. Results Compared with control group, diameter of the finger arterioles of T2DM patients were decreased significantly ([1.71±0.21]mm in T2DM group1,[1.59±0.25]mm in T2DM group 2,[2.11± 0.19]mm in control group, P<0.001), and Aflow of T2DM patients were diminished significantly ([62.18±10.31]mm2/s in T2DM group 1,[45.36±7.02]mm2/s in T2DM group 2,[75.32±11.97]mm2/s in control group, P<0.001). Aflow was lower in T2DM group 2 than that in T2DM group 1 with significant statistical differences (P<0.001). Conclusion Diameter of the finger arterioles and its flow parameters by quantitative three-dimensional Doppler spectrum might be a reliable noninvasive method to observe damage of peripheral arterioles in vivo, which could provide quantitative analysis for peripheral arterioles in patients with T2DM. |
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| Keywords: | Diabetes mellitus, type 2 Arteriole Ultrasonography |
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