| 帕瑞昔布钠复合舒芬太尼用于胸科术后患者静脉自控镇痛的观察 |
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| 引用本文： | 何娟,马虹.帕瑞昔布钠复合舒芬太尼用于胸科术后患者静脉自控镇痛的观察[J].临床麻醉学杂志,2011,27(3). |
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| 作者姓名： | 何娟 马虹 |
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| 作者单位： | 1. 郑州大学第一附属医院麻醉科
2. 中国医科大学附属第一医院麻醉科,沈阳市,110001 |
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| 摘 要： | 目的 观察帕瑞昔布钠对胸科术后患者静脉自控镇痛(PCIA)中舒芬太尼用量及镇痛效果的影响和安全性评价.方法 选择择期全麻下行开胸手术的患者40例,采用随机、双盲、对照研究,患者分为帕瑞昔布钠组(P组)和对照组(C组),P组在麻醉诱导时和诱导后12 h分别静注帕瑞昔布钠40 mg,C组给予等量生理盐水.术毕待患者清醒拔除气管导管后接镇痛泵.观察术后6、24、48 h舒芬太尼的用量、PCA按压总次数和有效次数.术后6 h(T<,1>)、24 h(T<,2>)、48 h(T<,3>)活动时VAS评分,记录不良反应及对镇痛效果的满意度.结果 与C组相比,T<,1>～T<,3>时P组显著减少了舒芬太尼的用量,T<,2>、T<,3>时PCA按压总次数和有效次数显著降低(P<0.01);T<,1>～T<,3>时P组运动时VAS评分显著降低(P<0.01).T<,3>时P组镇痛满意度为90%,明显高于C组的75%(P<0.05).结论 帕瑞昔布钠复合舒芬太尼用于胸科术后PCIA的镇痛效果优于单纯舒芬太尼,同时安全有效地减少术后镇痛泵中舒芬太尼的用量,提高患者术后镇痛质量.
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| 关 键 词： | 环氧化物酶-2抑制药 帕瑞昔布钠 舒芬太尼 自控静脉镇痛 |
The observation on effect of sufentanil with parecoxib for postoperative self-controlled intravenous analgesia in patients with thoracic surgery |
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| HE Juan,MA Hong.The observation on effect of sufentanil with parecoxib for postoperative self-controlled intravenous analgesia in patients with thoracic surgery[J].The Journal of Clinical Anesthesiology,2011,27(3). |
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| Authors: | HE Juan MA Hong |
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| Institution: | HE Juan,MA Hong.Department of Anesthesiology,First Affiliated Hospital of Chinese Medical University,Shenyang 110001,China |
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| Abstract: | Objective To observe the efficancy and safety of sufentanil with parecoxib sodium for intravenous analgesia after thoracic surgery.Methods Forty patients undergoing thoracic surgery with a standardized general anesthetic technique were randomly assigned to parecoxib group(group P)and control group(group C).group P:parecoxib 40 mg at induction and parecoxib 40 mg 12 h after induction;group C:normal saline at induction and 12 h after induction.After operation,the patients were awake and removed tracheal tube ... |
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| Keywords: | Cyclooxygenase-2 inhibitors Parecoxib Sufentanil Patient-controlled intravenous analgesia(PCIA) |
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