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| 七氟醚和丙泊酚对成人心电跨壁复极离散度的影响 | |
| 引用本文： | 陆志俊,沈亮,徐敏,郑慧敏,严瑾,于布为. 七氟醚和丙泊酚对成人心电跨壁复极离散度的影响[J]. 临床麻醉学杂志, 2011, 27(3) |
| 作者姓名： | 陆志俊 沈亮 徐敏 郑慧敏 严瑾 于布为 |
| 作者单位： | 1. 上海交通大学医学院附属瑞金医院麻醉科,200025 2. 上海交通大学医学院附属瑞金医院卢湾分院麻醉科 3. 上海交通大学医学院附属瑞金医院卢湾分院诊断科 |
| 摘 要： | 目的 比较吸入麻醉药七氟醚和静脉麻醉药丙泊酚对成人心电跨壁复极离散度的影响.方法 ASA Ⅰ或Ⅱ级择期普外科手术患者60例,男、女各30例.根据性别随机分为四组:女性七氟醚组(FS组),女性丙泊酚组(FP组),男性七氟醚组(MS组),男性丙泊酚组(MP组),每组患者均为15例,随机接受七氟醚或丙泊酚的麻醉诱导.麻醉诱导前行12导联同步ECG;检查为对照.FS、MS组采用8%七氟醚,氧气流量4 L/min诱导,七氟醚浓度以呼出浓度为准,入睡后七氟醚呼出浓度改为3%维持;FP、MP组采用丙泊酚靶控输注(TCI)诱导,血浆浓度3.5μg/ml.每组均采用BIS监测,以BIS值达45～50后维持15 min为观察终点,并获取麻醉诱导后12导联同步ECG.测量并记录麻醉诱导前后ECG的校正的QT间期(QTc间期)、T波峰-末间期(Tp-e间期)、HR、MAP、SpO<,2>.结果 七氟醚组(FS、MS组)麻醉诱导后QTc间期比诱导前延长(P<0.05),Tp-e间期差异无统计学意义;在丙泊酚组(FP、MP组)麻醉诱导前、诱导后QTc间期、Tp-e间期差异无统计学意义.结论 七氟醚延长患者QTc间期,但七氟醚和丙泊酚诱导对跨壁复极离散度不产生影响. |
| 关 键 词： | 跨壁复极离散度 QTc间期 七氟醚 丙泊酚 |
The effects of sevoflurane and propofol on transmural dispersion of repolarization in adults |
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| LU Zhi-jun,SHEN Liang,XU Min,et al.. The effects of sevoflurane and propofol on transmural dispersion of repolarization in adults[J]. The Journal of Clinical Anesthesiology, 2011, 27(3) | |
| Authors: | LU Zhi-jun SHEN Liang XU Min et al. |
| Affiliation: | LU Zhi-jun,SHEN Liang,XU Min,et al.Department of Anesthesiology,Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China |
| Abstract: | Objective To investigate the effects of sevoflurane and propofol on transmural dispersion of repolarization in adults.Methods Sixty patients were included in this study,thirty of them is male(Group M),the rest is female(Group F).For each gender,patients were randomly divided into two groups in which patients received propofol or sevoflurane,fifteen each.Group MS and MP meant male patients received sevoflurane or propofol.During anesthesia,end-tidal concentration of sevoflurane was maintained at 3% in patien... |
| Keywords: | Dispersion of repolarization QT interval Sevoflurane Propofol |
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