| 右美托咪定和丙泊酚用于硬膜外麻醉下妇科手术患者镇静的比较 |
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| 引用本文： | 梁永新,古妙宁,王世端,芦相玉. 右美托咪定和丙泊酚用于硬膜外麻醉下妇科手术患者镇静的比较[J]. 临床麻醉学杂志, 2011, 27(4) |
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| 作者姓名： | 梁永新 古妙宁 王世端 芦相玉 |
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| 作者单位： | 1. 青岛大学医学院附属医院麻醉科,266071
2. 南方医科大学南方医院麻醉科 |
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| 摘 要： | 目的 比较右美托咪定(Dex)和丙泊酚用于硬膜外麻醉下妇科手术患者的镇静效果.方法 硬膜外麻醉下择期行子宫或(和)卵巢切除患者100例,随机均分成Dex组(D组)和丙泊酚组(P组),应用Ramsay镇静评分和脑电双频指数(BIS)对两组患者术中镇静效果进行观察.记录给药前(T0)、切皮前即给药后15 min(T1)、手术开始后15 min(T2)、30 min(T3)、45 min(T4)、术毕(T5)及术后1 h(T6)患者HR、MAP、BIS、Ramsay镇静评分及呼吸抑制情况.结果 T1～T5时D组BIS,MAP明显低于T0时和P组,Ramsay镇静评分低于P组,HR慢于T0时和P组(P<0.05).低血压的发生率P组明显高于D组(P<0.05).结论 Dex用于硬膜外麻醉下妇科手术患者镇静是安全和可行的.
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| 关 键 词： | 右美托咪定 丙泊酚 镇静 硬膜外麻醉 脑电双频指数 |
A comparison of dexmedetomidine and propofol for sedation in gynecologic surgery under epidural anesthesia |
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| LIANG Yong-xin,GU Miao-ling,WANG Shi-duan,et al.. A comparison of dexmedetomidine and propofol for sedation in gynecologic surgery under epidural anesthesia[J]. The Journal of Clinical Anesthesiology, 2011, 27(4) |
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| Authors: | LIANG Yong-xin GU Miao-ling WANG Shi-duan et al. |
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| Affiliation: | LIANG Yong-xin,GU Miao-ling,WANG Shi-duan,et al.Department of Anesthesiology,Affiliated Hospital of Qingdao University Medical College,Qingdao 266071,China |
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| Abstract: | Objective To compare the sedative effect of dexmedetomidine and propofol in gynecologic surgery under epidural anesthesia.Methods One hundred female patients scheduled for oophorectomy or/and hysterectomy received epidural anesthesia in routine and were randomly assigned to two groups:Dexmedtomidine group(group D) and propofol group(group P).Ramsay sedation score(RASS) and bispectral index(BIS) values were used to observe the sedative effect of dexmedetomidine and propofol during surgery.In addition,HR,MAP,... |
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| Keywords: | Dexmedetomidine Propofol Sedation Epidural anesthesia Bispectral index |
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