刘寄奴黄酮类成分研究

目的:研究刘寄奴Artemisia anomala全草的化学成分。方法:柱色谱及高效液相色谱法分离其成分,波谱法鉴定其结构。结果:分离得到11个已知黄酮类化合物及2个黄酮木脂素类化合物,分别鉴定为山柰酚(1)、苜蓿素(2)、异泽兰黄素(3)、5,7,4′-三羟基-6,3′,5′-三甲氧基黄酮(4)、芒柄花素(5)、洋芹素(6)、柚皮素(7)、槲皮素(8)、毛蕊异黄酮(9)、芹菜素-7-O-葡萄糖苷(10)、山柰酚-3-O-芸香糖苷(11)、tricin 4′-O-(erythro-β-guaiacylglyceryl)ether(12)和tricin 4′-O-(threo-β-guai-acylglyceryl)ether(13)。结论:化合物12,13为首次从菊科中分离得到;化合物5,9为首次从蒿属中分离得到;化合物4,7,11为首次从该植物中分离得到。

Flavonoids from Artemisia anomala

Objective : To study the constituents of Artemisia anomala. Method : The constituents were isolated by chromatographic methods, their structures were elucidated by spectroscopic evidences. Result : Eleven flavonoids and two flavanolignans were purified and their structures were identified. Conclusion : Compound 12 and 13 were isolated from the Compositae family for the first time. Compound 5 and 9 were firstly isolated from the genus Artemisia. Compounds 4, 7, 11 were isolated from A. anomala for the first time.