胰腺囊实性假乳头状肿瘤6例临床病理学分析

目的；观察胰腺囊实性假乳头状肿瘤（CSTP）的临床病理及免疫组化特点及预后的关系。方法：6例CSTP常规石蜡切片、HE染色、免疫组化（S—P）法染色观察。结果：6例术后无复发，肿瘤较大，大部有包膜，由实性与囊性坏死组织组成。镜下见肿瘤细胞形态大小较一致，核圆形或卵圆形，核异型性不明显，核分裂象少见，可见肿瘤细胞绕血管成乳头状排列。免疫组化：6例AACT（＋）、Vimentin（＋），4例NSE（＋），SMA、S-100，均阴性。结论：胰腺囊实性假乳头状肿瘤（CSTP）是好发生于年轻女性的低度恶性肿瘤，手术切除有较高的治愈率。

The analysis of clinicopathological features in 6cases of pancreas solid-cysticpseudopapillary tumor

Objective To investigate the immunohistochemical features of solid-cystic＂ pseudopapillary tumor in pancreas （SCPT） and impacts on clinical prognosis. Methods Samples collected from 6cases of CSTP were stained by histological （H-E stains） and immunohistochemical method （S-P method） Results： All the 6 patients were recovered without recurrence after tumor resection. The tumors were large in size and great messily allencapsulated. The section of the tumor showed solid altemately with cystic. The microscopy observation showed tumor cells were in uniform, the nuclei were oval, round without magnificent alypia and mitotic were rarely to find. The tumor cells were arrayed in Psudopapillary structure with a fibrovascular core. Immunohistochemical results were as bellow： the tumor cells were neg- ative in Des. S-100, and were positive in Syn, Vimentin（＋）, EMA（-）;additionally 6cases AACT（＋）, 4cases NSE（＋）, 6case Vimentin（＋）,. Conclusion： SCPT is a low potential malignancy tumor and found most frequently in middle-aged women without recurrence after tumor resection.