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渗透性脱髓鞘综合征
引用本文:蒋雯巍,蒋雨平. 渗透性脱髓鞘综合征[J]. 中国临床神经科学, 2007, 15(3): 306-309
作者姓名:蒋雯巍  蒋雨平
作者单位:1. 复旦大学附属华山医院老年科,200040
2. 复旦大学附属华山医院神经科,200040
摘    要:渗透性脱髓鞘综合征是由于慢性低钠血症患者,予以迅速补钠,改变低渗状态,造成有毒损害。渗透性脱髓鞘综合征的临床表现有脑桥中央髓鞘溶解症、脑桥外髓鞘溶解症。本文复习了渗透性脱髓鞘综合征的临床、病因和病理并作介绍。

关 键 词:渗透性脱髓鞘综合征  脑桥中央髓鞘溶解症  脑桥外髓鞘溶解症  临床表现
文章编号:1008-0678(2007)03-0306-04
修稿时间:2007-03-02

Osmotic Demyelination Syndrome
JIANG Wen-Wei,JIANG Yu-Ping. Osmotic Demyelination Syndrome[J]. Chinese Journal of Clinical Neurosciences, 2007, 15(3): 306-309
Authors:JIANG Wen-Wei  JIANG Yu-Ping
Abstract:The osmotic demyelination syndrome is a complication of treatment of patients with profound, lift threatening hyponatraemia. It occurs as a conseguence of a rapid rise in serum tonicity in individuals with chronic severe hyponatraemia who have made intracellular adaptations to the prevailing hypotonicity. Elevating in serum sodium is the overwhelming contributor to the rise in tonicity. Clinical manifestations of osmotic demyelination syndrome include a central pontine myelinolysis and an extrapontine myelinolysis mainly. In this review we discuss the clinical, pathological, and etiological features of the syndrome.
Keywords:osmotic demyelination syndrome  central pontine myelinotysis  extrapotine myelinolysis  clinical manifestation
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