急性脑卒中后睡眠障碍患者药物治疗联合心理干预效果评价?

目的：观察药物治疗联合心理治疗对脑卒中后睡眠障碍患者的临床疗效。方法选择符合条件的180例睡眠障碍患者,分为对照组和治疗组两组。对照组进行常规血管药物治疗,舒乐安定片2 mg,睡前服；治疗组在对照组治疗的基础上给予抗焦虑及镇静催眠药(文拉法辛、右佐匹克隆)；治疗14 d 后组内、两组间比较治疗前后睡眠质量、神经功能缺损程度等。结果两组间及治疗组治疗前后患者 Barthel 指数、NIHSS 及 PSQI 比较,差异有统计学意义(P <0.05)。结论在常规脑血管药物基础上结合文拉法辛、右佐匹克隆及心理治疗能显著改善脑卒中患者的睡眠质量。

The effect evaluation of medicine treatment combined with psychological intervention for sleep disorders patients after acute brain stroke

Objective To observe the clinical curative effect of drug combined with psychological treatment on patients with sleep disorders after stroke.Methods A total of 180 cases of eligible patients with sleep disorders were included and randomly di-vided into control group and treatment group.Control group were treated with conventional vascular drug(estazolam,2 mg,before sleep);treatment group increased anxiolytic and sedative hypnotic drugs(venlafaxine,dexzopiclone)compared to control group.Af-ter 14 days,sleep quality,NIHSS were compared both within the treatment group and between the two groups.Results The Bar-thel index,NIHSS and PSQI of two groups had significant differences,and those index of treatment group before and after treat-ment had significant differences too(P <0.05).Conclusion Combined conventional cerebrovascular drugs with Venlafaxine,dexzo-piclone as well as psychological treatment significantly improved sleep quality of patients with acute stroke.