10例经导管肾动脉交感神经射频消融术治疗顽固性高血压 |
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引用本文: | 黄国鹏,许中恒,彭亚,陶黎,宋文信.10例经导管肾动脉交感神经射频消融术治疗顽固性高血压[J].重庆医学,2015(22):3068-3069. |
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作者姓名: | 黄国鹏 许中恒 彭亚 陶黎 宋文信 |
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作者单位: | 重庆市大足区人民医院心内科 402360 |
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摘 要: | 目的:探讨经导管肾动脉交感神经射频消融术(RDN)治疗顽固性高血压的临床疗效。方法回顾性分析10例经RDN 治疗的顽固性高血压患者的临床资料,分析 RDN 治疗后患者血压的变化及并发症情况。结果患者术后2周收缩压、舒张压均较术前明显下降,术后3个月进一步下降,差异均有统计学意义(P <0.05),术后6个月与术后3个月比较差异无统计学意义(P >0.05);术前平均应用降压药种数为(5.3±0.9)种,术后6个月随诊平均用药种类(3.2±0.6)种,较术前明显减少,差异有统计学意义(P <0.05)。患者未出现不良反应。结论RDN 可迅速、持续地降低顽固性高血压患者的血压水平,具有较好的安全性。
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关 键 词: | 高血压 交感神经系统 肾动脉 血压 导管消融术 |
Clinical effect of 10 patients with resistant hypertension treated by transcatheter renal sympathetic denervation |
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Abstract: | Objective To evaluate the clinical efficacy of transcatheter renal sympathetic denervation(RDN)in the treatment of resistant hypertension.Methods Clinical data of 10 patients with resistant hypertension treated by transcatheter renal sympa-thetic denervation were retrospectively analyzed.The blood pressure and complications were analyzed.Results In all of the 10 pa-tients,systolic and diastolic blood pressure decreased significantly after two weeks compared with preoperative,and further de-creased after 3 months (P <0.05 ).There were no statistical difference of systolic and diastolic blood pressure between 3 and 6 months(P >0.05).Before the RDN,the mean number of antihypertensive drugs was 5.3±0.9.After 6 months which was 3.2±0. 6,and which was decreased significantly compared with the preoperative (P <0.05).No adverse reactions were found.Conclusion The RDN can be quickly and sustained decrease the blood pressure in patients with resistant hypertension. |
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Keywords: | hypertension sympathetic nervous system renal artery blood pressure catheter ablation |
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