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Apolipoprotein E4 and tau allele frequencies among Choctaw Indians
Authors:Henderson J Neil  Crook Richard  Crook Julia  Hardy John  Onstead Luisa  Carson-Henderson Linda  Mayer Pat  Parker Bea  Petersen Ronald  Williams Birdie
Affiliation:Department of Health Promotion Sciences, University of Oklahoma, Oklahoma City 73190, USA.
Abstract:Apolipoprotein genotyping and tau haplotyping were carried out on a series of cases with dementia and controls from the Choctaw Nation of Oklahoma. Both the Apolipoprotein E4 allele frequency and the tau H2 haplotype frequency were low in the Choctaw compared with Caucasians and there was the possibility that the association between dementia and the E4 allele was weaker than in Caucasians.
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