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依巴斯汀治疗冬季皮肤瘙痒症的疗效观察
引用本文:徐翔,梁东辉,李建勤,马红利,袁苏健.依巴斯汀治疗冬季皮肤瘙痒症的疗效观察[J].药物流行病学杂志,2010(3):124-125,137.
作者姓名:徐翔  梁东辉  李建勤  马红利  袁苏健
作者单位:长江航运总医院皮肤科;
摘    要:目的:观察依巴斯汀片治疗冬季皮肤瘙痒症的疗效和安全性。方法:采用随机对照和意向性分析的研究。观察组口服依巴斯汀片10mg·d^-1,对照组口服酮替芬片1mg·d^-1,两组均外搽2%樟脑霜。21d为1疗程。结果:观察组的总有效率86.05%,对照组62.79%,两组比较P〈0.05。两组药品不良反应差异有统计学意义(P〈0.005)。结论:依巴斯汀片治疗冬季皮肤瘙痒症的疗效肯定且安全。

关 键 词:瘙痒症/冬季  依巴斯汀  酮替芬

Study of Ebastine in Treating Pruritus Hiemalis
Xu Xiang,Liang Donghui,Li Jianqin,Ma Hongli,Yuan Sujian Changhang General Hospital,Wuhan,China.Study of Ebastine in Treating Pruritus Hiemalis[J].Chinese Journal of Pharmacoepidemiology,2010(3):124-125,137.
Authors:Xu Xiang  Liang Donghui  Li Jianqin  Ma Hongli  Yuan Sujian Changhang General Hospital  Wuhan  China
Institution:Xu Xiang,Liang Donghui,Li Jianqin,Ma Hongli,Yuan Sujian Changhang General Hospital,Wuhan 430010,China
Abstract:Objective:To study the effect and safety of ebastine in the treatment of pruritus hiemalis.Methods: In the randomized controlled study and by an intention-to-treat analysis(ITT),the test unit was treated with ebastine 10mg for a day,the controlled group,treated with ketotifen 1 mg for a day,and both units took 2%camphor cream.Results:The effect rate of the test unit was 86.05%and that of the controlled group was 62.79%,P<0.05.Adverse drug reactions of the two groups showed significantly statistical differen...
Keywords:Pruritus hiemalis  Ebastine  Ketotifen  
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