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The effect of melatonin on sedation of children undergoing magnetic resonance imaging |
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| Authors: | Sury M R J Fairweather K |
| Affiliation: | 1 Department of Anaesthesia, Great Ormond Street Hospital for Children NHS Trust London WC1N 3JH, UK 2 Department of Radiology, Great Ormond Street Hospital for Children NHS Trust London WC1N 3JH, UK 3 Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health 30 Guilford Street, London WC1N 1EH, UK |
| Abstract: | Background. Melatonin may induce a natural sleepiness and improvepredictability of sedation drugs. We have investigated its clinicalvalue in children sedated for magnetic resonance imaging. Methods. In a stratified randomized double-blind study, 98 childrenreceived either melatonin or placebo 10 min before they weresedated with a standard oral regimen. Children >5 and <15kg received chloral hydrate and those |
| Keywords: | brain, magnetic resonance imaging hormones, melatonin paediatrics sedation, deep sedation |
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