Immune restoration disease and changes in CD4+ T-cell count in HIV- infected patients during highly active antiretroviral therapy at Zewditu memorial hospital,Addis Ababa,Ethiopia |
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| Authors: | Kahsay Huruy Afework Kassu Andargachew Mulu Yemataw Wondie |
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| Affiliation: | (1) Department of Medical Laboratory Technology, College of Medicine and Health Sciences, University of Gondar, Ethiopia;(2) Institute of Virology, Faculty of Medicine, University of Leipzig, Germany;(3) Department of Microbiology and Parasitology, College of Medicine and Health Sciences, University of Gondar, Ethiopia;(4) Division of Allergy and Clinical Immunology, Department of Medicine, University of Colorado, Denver, USA;(5) Faculty of Social Sciences and Humanities, University of Gondar, Gondar, Ethiopia;(6) Institute of Psychology II, Clinical and Health Psychology, University of Leipzig, Germany |
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| Abstract: | Background Highly active antiretroviral therapy (HAART) improves the immune function and decreases morbidity, mortality and opportunistic infections (OIs) in HIV-infected patients. However, since the use of HAART, immune restoration disease (IRD) has been described in association with many OIs. Our objective was to determine the proportion of IRD, changes in CD4+ T-cell count and possible risk factors of IRD in HIV-infected patients. |
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