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Assignment of the linkage group EAM-TYRP2-TPP2 to chromosome 11 in pigs byin situ hybridization mapping of the TPP2 gene |
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| Authors: | B. P. Chowdhary M. Johansson F. Gu P. Bräuner-Nielsen B. Tomkinson L. Andersson I. Gustavsson |
| Affiliation: | (1) the Department of Animal Breeding and Genetics, Swedish Agricultural University, Box 7023, S-750 07 Uppsala, Sweden;(2) the Department of Anatomy and Physiology, The Royal Veterinary and Agricultural University, Bülowsvej 13, 1870 Fredriksberg C, Denmark;(3) the Department of Veterinary Medical Chemistry, Swedish Agricultural University, Box 575, S-751 23 Uppsala, Sweden |
| Abstract: | Restriction fragment length polymorphisms are described for the genes coding for tripeptidyl peptidase II (TPP2) and tyrosinase related protein II (TYRP2) in pigs. A linkage group comprising these loci and the locus for blood group M (EAM) was established by two-point lod score analysis in a three-generation pedigree. Multipoint analysis indicated the linear order EAM-1.1-TYRP2-8.4-TPP2 (recombination distances are given as Kosambi cM). The linkage group was assigned to porcine chromosome 11—the first on this chromosome—throughin situ hybridization mapping of the TPP2 gene. TPP2 is the first gene localized on this chromosome usingin situ hybridization. |
| Keywords: | In situ hybridization mapping TPP2 porcine chromosome II Sus scrofa domestica |
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