静脉肾盂造影未显影的肾脏行^99Tc^m-喷替酸盐肾动态显像检测GFR价值

目的泌尿系疾病患者行常规的静脉肾盂造影（IVP）检查结果为肾不显影时,进一步行肾动态显像来定量测定肾小球滤过率（glom eru lar filtration rate,GFR）的意义。方法将研究对象分为3组：IVP不显影组为76例（37例左肾,39例右肾）,其IVP检查为单侧肾脏肾盏肾盂及输尿管不显影,正常对照组为57例肾移植供体,阳性对照组为12例肾功能不全尿毒症期患者,均采用锝-99m-喷替酸盐（99Tcm-DTPA）肾动态显像Gates法计算其GFR,并通过多个独立样本的非参数秩和检验进行统计分析。结果 IVP不显影组中,左肾GFR为：（18.73±9.33）m l/（min.1.73 m2）,右肾GFR值为：（16.71±7.02）m l/（min.1.73 m2）;正常对照组左肾GFR值为：（43.41±7.40）m l/（min.1.73 m2）,右肾GFR值为：（45.37±8.07）m l/（min.1.73 m2）;阳性对照组GFR值为：左肾GFR值为：（6.84±3.81）m l/（min.1.73 m2）,右肾GFR值为：（7.08±4.75）m l/（min.1.73 m2）;3组间存在显著性差异（P〈0.01）。结论 IVP检查结果为肾不显影时,仍然需要进一步行肾动态显像来定量其单侧GFR,这对临床治疗决策具有指导意义。

Determination of glomerular filtration rate by 99Tcm-DTPA nephro-dynamic imaging in patients with nonvisualization in intravenous pyelography

Objective To investigate the significance of detection of the glomerular filtration rate(GFR)by 99Tcm-diethylenetriaminepentaacetic acid(DTPA)nephro-dynamic imaging in patients with nonvisualization in routine intravenous pyelography(IVP).Methods Subjects were classified into three groups:IVP-nonvisualization group including 76 patients with unilateral pelvicaliceal and ureteral nonvisualization,normal control group including 57 renal transplant donors,and positive control group including 12 uremic patients...