活力苏治疗抑郁症中睡眠障碍的疗效观察

目的 评定活力苏治疗抑郁症中睡眠障碍的疗效。方法 将抑郁症患者随机分为研究与对照组。研究组合并使用选择性5－HT回收抑制剂（SSRI）阿普唑伦和活力苏；对照组使用SSRI，阿普唑伦，评定工具为症状自评量表（SCL－90），流调中心用抑郁量有（CES－D），焦虑自评量表（SAS），抑郁自评量表（SDS）和匹滋堡睡眠质量量表（PSQI），结果 两组治疗前后的总分和人际关系，抑郁，焦虑，敌对，恐怖，偏执，精神病性均有显著改善。研究组的躯体化因子治疗前后显著改变，而对照组无。研究组除睡眠总分，睡眠质量及睡眠障碍外，还有睡眠时间，日间功能障碍的显著改善。结论 活力苏能够明显地改善抑郁症患者的睡眠质量。

THE OBSERVATION ON HUOLISU'S EFFICACY IN CURING SLEEP DISTURBANCE OF DEPRESSION

OBJECTIVE To study Huolisu's efficacy in curing sleep disturbance of depression. METHODS The depression patients were assigned randomly to study group and control group. The control group taked SSRI and aprazolam The study group was added Huolisu on the basis of the control group.SCL 90,CES-D and PSQI were used to evaluate the curative effect before and after treatment.RESULTS There was significant improvement on some factors in the two groups after treatment.These factors included total SCL-90, interpersonal sensitivity,depression,anxiety,hostility,photic anxiety,paranoid ideation and psychoticism.After treatment,the study group improved significantly not only on somatization,but also on some factors of PSQI,which included total PSQI, subjective sleep quality,sleep disturbance, sleep duration and daytime dysfunction.CONCLUSION Huolisu can improve significantly subjective sleep quality in the depression patients.