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Lead toxicity masquerading as sickle cell crisis
Authors:M S Nelson  J J Chisolm
Affiliation:1. Department of Microbiology, CHU La Reunion, St Pierre, France;2. UMR PIMIT « processus infectieux en milieu insulaire tropical », Inserm 1187, CNRS 9192, IRD 249, université de La Réunion, CYROI, 97490 Sainte-Clotilde, Reunion;3. University of Brest, GEIHP EA, 3142, Brest, France;4. Department of Hematology and Medical Oncology, CHU La Reunion, St Pierre, France;5. Department of Infectious Diseases, CHU La Reunion, St Pierre, France;6. Intensive Care Unit, CHU La Reunion, St Pierre, France;1. Infection Prevention, Health Services Advisory Group, Inc, Glendale, CA;2. Faculty, West Coast University, Los Angeles, CA;3. Infection Prevention & Management Associates, Inc, Houston, TX
Abstract:We recently saw a 12-year-old black boy with known sickle cell disease who had been seen many times for abdominal pain thought to be secondary to a vasoocclusive crisis. The patient eventually was admitted, after a seizure and the onset of obtundation. The etiology of his acute encephalopathy remained unclear until bone films of his knees fortuitously revealed "lead lines." The patient was treated and did well subsequently. This case emphasizes the importance of considering other diagnoses when a sickle cell patient presents with a crisis.
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