长期家庭氧疗对慢性阻塞性肺疾病患者心理情绪的影响

目的探讨长期家庭氧疗(LTOT)对慢性阻塞性肺疾病(COPD)低氧血症患者心理情绪的影响。方法 31例COPD低氧血症患者用医院焦虑和抑郁情绪表(HAD)进行心理情绪评分。然后分为LTOT组17例和对照组14例。LTOT组的氧流量0.5～2.5L/min，每日吸氧时间≥15h(包括睡眠时间)；对照组除未进行LTOT外，其余治疗与氧疗组相同。两组年龄、性别、肺功能和动脉血气无明显差别。1年后分别复查HAD评分。结果 LTOT组焦虑评分由治疗前的14.35±3.81下降到1年后的9.65±3.83(P<0.01)，抑郁评分由治疗前的13.18±4.50下降到1年后的9.06±2.79(P<0.01)；对照组焦虑和抑郁评分均无明显变化。1年后LTOT组的焦虑及抑郁评分分别与对照组比较明显改善。1年后LTOT组除动脉血氧分压与对照组有显著差异外，动脉血二氧化碳分压、PH值及肺功能均无显著差异。结论 LTOT能改善COPD低氧血症患者的心理情绪。

The psychological effects of long term domicilinary oxygen therapy on stable chronic obstructive pulmonary disease with hypoxaemia

Objective　To observe the psychological effects of long term domicilinary oxygen therapy (LTOT) on stable chronic obstructive pulmonary disease(COPD) with hypoxaemia.Method　Thirty one hypoxaemic patients with stable COPD were divided into two groups(LTOT group and control group).The hospital anxiety depression score(HAD) were evaluated in both groups.LTOT groups were received oxygen therapy with the flow of 0.5～2.5 L/min for 15hrs or more every day in one year,The control group were received regular treatment except LTOT.In both groups the HAD score were evaluated after one year again.Results　HAD-A score in LTOT group were significantly declined from 14.35±3.81 to 9.65±3.82(P<0.01), the HAD-D score were also significantly declined from 13.18±4.50 to 9.06±2.79(P<0.01);but in the control group neither score was improved.Conclusion　LTOT could improve psychological status in stable COPD with hypoxaemia.